[HTML][HTML] Triple-negative breast cancer—current status and future directions
Triple-negative breast cancer (TNBC) is defined by a lack of expression of both estrogen
and progesterone receptor as well as human epidermal growth factor receptor 2. It is …
and progesterone receptor as well as human epidermal growth factor receptor 2. It is …
Progress and pitfalls in the use of immunotherapy for patients with triple negative breast cancer
E Agostinetto, A Losurdo, G Nader-Marta… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Triple negative breast cancer (TNBC) is an area of high unmet medical need in
terms of new effective treatment strategies. Although breast cancer is traditionally …
terms of new effective treatment strategies. Although breast cancer is traditionally …
Detachable liposomes combined immunochemotherapy for enhanced triple-negative breast cancer treatment through reprogramming of tumor-associated …
M Chen, Y Miao, K Qian, X Zhou, L Guo, Y Qiu… - Nano …, 2021 - ACS Publications
Triple-negative breast cancer (TNBC) is an aggressive disease with a high recurrence rate
and poor outcomes in clinic. In this study, inspired by the enriched innate immune cell type …
and poor outcomes in clinic. In this study, inspired by the enriched innate immune cell type …
The influence of socioeconomic disparities on breast cancer tumor biology and prognosis: a review
L Vona-Davis, DP Rose - Journal of women's health, 2009 - liebertpub.com
Objective: Socioeconomic deprivation is associated with an increased risk of breast cancer
mortality. This article summarizes the relationships between socioeconomic status (SES) …
mortality. This article summarizes the relationships between socioeconomic status (SES) …
Combined SFK/MEK inhibition prevents metastatic outgrowth of dormant tumor cells
LH El Touny, A Vieira, A Mendoza… - The Journal of …, 2014 - Am Soc Clin Investig
Breast cancer (BC) can recur as metastatic disease many years after primary tumor removal,
suggesting that disseminated tumor cells survive for extended periods in a dormant state …
suggesting that disseminated tumor cells survive for extended periods in a dormant state …
High ERK protein expression levels correlate with shorter survival in triple-negative breast cancer patients
C Bartholomeusz, AM Gonzalez-Angulo, P Liu… - The …, 2012 - academic.oup.com
The mitogen-activated protein kinase (MAPK) signaling pathway is known to be activated in
triple-negative breast cancer (TNBC). Extracellular signal–related kinase (ERK), a member …
triple-negative breast cancer (TNBC). Extracellular signal–related kinase (ERK), a member …
[PDF][PDF] PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer
X Wang, J Yu, X Liu, D Luo, Y Li, L Song, X Jiang… - Cell Reports …, 2022 - cell.com
Although the MAPK pathway is aberrantly activated in triple-negative breast cancers
(TNBCs), the clinical outcome of MEK-targeted therapy is still poor. Through a genome-wide …
(TNBCs), the clinical outcome of MEK-targeted therapy is still poor. Through a genome-wide …
The mitotic kinase Aurora-A promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα+ breast cancer cells
AB D'assoro, C Quatraro, A Amato, M Opyrchal… - Oncogene, 2014 - nature.com
In this study, we demonstrate that constitutive activation of Raf-1 oncogenic signaling
induces stabilization and accumulation of Aurora-A mitotic kinase that ultimately drives the …
induces stabilization and accumulation of Aurora-A mitotic kinase that ultimately drives the …
Chrysin inhibits metastatic potential of human triple‐negative breast cancer cells by modulating matrix metalloproteinase‐10, epithelial to mesenchymal transition, and …
Chrysin, a naturally occurring flavone, has been shown to inhibit cell proliferation and
induce cell apoptosis in various cancers. However, the effect and mechanisms of chrysin on …
induce cell apoptosis in various cancers. However, the effect and mechanisms of chrysin on …
[HTML][HTML] Curcumin induces apoptosis of triple-negative breast cancer cells by inhibition of EGFR expression
XD Sun, XE Liu, DS Huang - Molecular medicine …, 2012 - spandidos-publications.com
Curcumin is the major component of the spice turmeric, extracted from the rhizomes of the
plant Curcuma longa. It exerts a number of therapeutic effects, including the inhibition of …
plant Curcuma longa. It exerts a number of therapeutic effects, including the inhibition of …