Triple-negative breast cancer (TNBC) is defined by a lack of expression of both estrogen
and progesterone receptor as well as human epidermal growth factor receptor 2. It is …

Introduction Triple negative breast cancer (TNBC) is an area of high unmet medical need in
terms of new effective treatment strategies. Although breast cancer is traditionally …

Triple-negative breast cancer (TNBC) is an aggressive disease with a high recurrence rate
and poor outcomes in clinic. In this study, inspired by the enriched innate immune cell type …

Objective: Socioeconomic deprivation is associated with an increased risk of breast cancer
mortality. This article summarizes the relationships between socioeconomic status (SES) …

Breast cancer (BC) can recur as metastatic disease many years after primary tumor removal,
suggesting that disseminated tumor cells survive for extended periods in a dormant state …

The mitogen-activated protein kinase (MAPK) signaling pathway is known to be activated in
triple-negative breast cancer (TNBC). Extracellular signal–related kinase (ERK), a member …

Although the MAPK pathway is aberrantly activated in triple-negative breast cancers
(TNBCs), the clinical outcome of MEK-targeted therapy is still poor. Through a genome-wide …

In this study, we demonstrate that constitutive activation of Raf-1 oncogenic signaling
induces stabilization and accumulation of Aurora-A mitotic kinase that ultimately drives the …

Chrysin, a naturally occurring flavone, has been shown to inhibit cell proliferation and
induce cell apoptosis in various cancers. However, the effect and mechanisms of chrysin on …

Curcumin is the major component of the spice turmeric, extracted from the rhizomes of the
plant Curcuma longa. It exerts a number of therapeutic effects, including the inhibition of …