[HTML][HTML] Mechanisms of macular edema: beyond the surface
Macular edema consists of intra-or subretinal fluid accumulation in the macular region. It
occurs during the course of numerous retinal disorders and can cause severe impairment of …
occurs during the course of numerous retinal disorders and can cause severe impairment of …
Involvement of advanced glycation end products in the pathogenesis of diabetic retinopathy
J Xu, LJ Chen, J Yu, HJ Wang, F Zhang… - Cellular Physiology and …, 2018 - karger.com
Diabetic retinopathy (DR) is a common and devastating microvascular complication of
diabetes and a major cause of acquired blindness in young adults. Advanced glycation end …
diabetes and a major cause of acquired blindness in young adults. Advanced glycation end …
[HTML][HTML] Exploring the choroidal vascular labyrinth and its molecular and structural roles in health and disease
J Brinks, EHC Van Dijk, I Klaassen… - Progress in retinal and …, 2022 - Elsevier
The choroid is a key player in maintaining ocular homeostasis and plays a role in a variety of
chorioretinal diseases, many of which are poorly understood. Recent advances in the field of …
chorioretinal diseases, many of which are poorly understood. Recent advances in the field of …
Sulodexide prevents activation of the PLA2/COX-2/VEGF inflammatory pathway in human retinal endothelial cells by blocking the effect of AGE/RAGE
G Giurdanella, F Lazzara, N Caporarello, G Lupo… - Biochemical …, 2017 - Elsevier
Diabetic retinopathy is characterized by the breakdown of endothelial blood-retinal barrier.
We tested the hypothesis that sulodexide (SDX), a highly purified glycosaminoglycan …
We tested the hypothesis that sulodexide (SDX), a highly purified glycosaminoglycan …
miR-15a/16 reduces retinal leukostasis through decreased pro-inflammatory signaling
EA Ye, L Liu, Y Jiang, J Jan, S Gaddipati… - Journal of …, 2016 - Springer
Background Hyperglycemia is a significant risk factor for diabetic retinopathy and induces
increased inflammatory responses and retinal leukostasis, as well as vascular damage …
increased inflammatory responses and retinal leukostasis, as well as vascular damage …
A revised hemodynamic theory of age-related macular degeneration
BD Gelfand, J Ambati - Trends in molecular medicine, 2016 - cell.com
Age-related macular degeneration (AMD) afflicts one out of every 40 individuals worldwide,
causing irreversible central blindness in millions. The transformation of various tissue layers …
causing irreversible central blindness in millions. The transformation of various tissue layers …
A review of therapies for diabetic macular oedema and rationale for combination therapy
WMK Amoaku, S Saker, EA Stewart - Eye, 2015 - nature.com
Diabetic macular oedema (DMO) is responsible for significant visual impairment in diabetic
patients. The primary cause of DMO is fluid leakage resulting from increased vascular …
patients. The primary cause of DMO is fluid leakage resulting from increased vascular …
Differentially expressed microRNAs in the development of early diabetic retinopathy
Q Gong, J Xie, Y Liu, Y Li, G Su - Journal of diabetes research, 2017 - Wiley Online Library
The pathological mechanisms of diabetic retinopathy (DR), a leading cause of blindness in
adults with diabetes mellitus, remain incompletely understood. Because microRNAs …
adults with diabetes mellitus, remain incompletely understood. Because microRNAs …
Барьерная функция эндотелия, механизмы ее регуляции и нарушения
АН Иванов, ДМ Пучиньян, ИА Норкин - Успехи физиологических наук, 2015 - elibrary.ru
Эндотелий является важным регулятором избирательной проницаемости сосудистой
стенки для различных веществ и клеток. В обзоре представлены современные данные …
стенки для различных веществ и клеток. В обзоре представлены современные данные …
The different facades of retinal and choroidal endothelial cells in response to hypoxia
E Alizadeh, P Mammadzada, H André - International journal of molecular …, 2018 - mdpi.com
Ocular angiogenic diseases, such as proliferative diabetic retinopathy and neovascular age-
related macular degeneration, are associated with severe loss of vision. These pathologies …
related macular degeneration, are associated with severe loss of vision. These pathologies …