The SARS-CoV-2 nucleocapsid protein: its role in the viral life cycle, structure and functions, and use as a potential target in the development of vaccines and …

W Wu, Y Cheng, H Zhou, C Sun, S Zhang - Virology journal, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) continues to take a heavy toll on personal
health, healthcare systems, and economies around the globe. Scientists are expending …

SARS-CoV-2 and the spike protein in endotheliopathy

L Perico, A Benigni, G Remuzzi - Trends in Microbiology, 2024 - cell.com
Abstract SARS-CoV-2, the causative agent of COVID-19, primarily affects the epithelial
compartment in the upper and lower airways. There is evidence that the microvasculature in …

Persistent circulating severe acute respiratory syndrome coronavirus 2 spike is associated with post-acute coronavirus disease 2019 sequelae

Z Swank, Y Senussi, Z Manickas-Hill… - Clinical Infectious …, 2023 - academic.oup.com
The diagnosis of postacute sequelae of coronavirus disease 2019 (PASC) poses an
ongoing medical challenge. To identify biomarkers associated with PASC we analyzed …

[HTML][HTML] Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination

K Röltgen, SCA Nielsen, O Silva, SF Younes… - Cell, 2022 - cell.com
During the SARS-CoV-2 pandemic, novel and traditional vaccine strategies have been
deployed globally. We investigated whether antibodies stimulated by mRNA vaccination …

Circulating spike protein detected in post–COVID-19 mRNA vaccine myocarditis

LM Yonker, Z Swank, YC Bartsch, MD Burns, A Kane… - Circulation, 2023 - Am Heart Assoc
Background: Cases of adolescents and young adults developing myocarditis after
vaccination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–targeted …

Accelerated biological aging in COVID-19 patients

X Cao, W Li, T Wang, D Ran, V Davalos… - Nature …, 2022 - nature.com
Chronological age is a risk factor for SARS-CoV-2 infection and severe COVID-19. Previous
findings indicate that epigenetic age could be altered in viral infection. However, the …

[HTML][HTML] Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier

LM Yonker, T Gilboa, AF Ogata… - The Journal of …, 2021 - Am Soc Clin Investig
Multisystem inflammatory syndrome in children (MIS-C) occurs during or recently following
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and is …

Circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine antigen detected in the plasma of mRNA-1273 vaccine recipients

AF Ogata, CA Cheng, M Desjardins… - Clinical Infectious …, 2022 - academic.oup.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins were measured in
longitudinal plasma samples collected from 13 participants who received two doses of …

Persistent circulating SARS-CoV-2 spike is associated with post-acute COVID-19 sequelae

Z Swank, Y Senussi, G Alter, DR Walt - Medrxiv, 2022 - medrxiv.org
The diagnosis and management of post-acute sequelae of COVID-19 (PASC) poses an
ongoing medical challenge. Identifying biomarkers associated with PASC would immensely …

COVID-19 antibody tests and their limitations

G Liu, JF Rusling - ACS sensors, 2021 - ACS Publications
COVID-19, caused by the SARS-CoV-2 virus, has developed into a global health crisis,
causing over 2 million deaths and changing people's daily life the world over. Current main …