Vitamin C and immune cell function in inflammation and cancer

A Ang, JM Pullar, MJ Currie… - Biochemical Society …, 2018 - portlandpress.com
Vitamin C (ascorbate) is maintained at high levels in most immune cells and can affect many
aspects of the immune response. Intracellular levels generally respond to variations in …

[HTML][HTML] Vitamin C supplementation in the treatment of autoimmune and onco-hematological diseases: from prophylaxis to adjuvant therapy

S Isola, L Gammeri, F Furci, S Gangemi… - International Journal of …, 2024 - mdpi.com
Vitamin C is a water-soluble vitamin introduced through the diet with anti-inflammatory,
immunoregulatory, and antioxidant activities. Today, this vitamin is integrated into the …

Metabolism in acute myeloid leukemia: mechanistic insights and therapeutic targets

SK Mishra, SE Millman, L Zhang - Blood, 2023 - ashpublications.org
Metabolic rewiring and cellular reprogramming are trademarks of neoplastic initiation and
progression in acute myeloid leukemia (AML). Metabolic alteration in leukemic cells is often …

Vitamin C transporters and their implications in carcinogenesis

K Linowiecka, M Foksinski, AA Brożyna - Nutrients, 2020 - mdpi.com
Vitamin C is implicated in various bodily functions due to its unique properties in redox
homeostasis. Moreover, vitamin C also plays a great role in restoring the activity of 2 …

Vitamin C plasma levels associated with inflammatory biomarkers, CRP and RDW: results from the NHANES 2003–2006 surveys

JM Crook, AL Horgas, SL Yoon, O Grundmann… - Nutrients, 2022 - mdpi.com
Although undisputed for its anti-inflammatory and immune system boosting properties,
vitamin C remains an inconsistently investigated nutrient in the United States. However …

Vitamin C deficiency in patients with acute myeloid leukemia: A case series and review of the literature

HC Milbar, A Caplan, RD Schwab… - Blood …, 2023 - ashpublications.org
Vitamin C (Vc) deficiency is characterized by an array of mucocutaneous findings, including
ecchymoses, petechiae, perifollicular hemorrhage, oral ulcerations, gingival hypertrophy …

The level of active DNA demethylation compounds in leukocytes and urine samples as potential epigenetic biomarkers in breast cancer patients

K Linowiecka, J Guz, T Dziaman… - Scientific Reports, 2024 - nature.com
The active DNA demethylation process, which involves TET proteins, can affect DNA
methylation pattern. TET dependent demethylation results in DNA hypomethylation by …

[HTML][HTML] Unlocking the Heterogeneity in Acute Leukaemia: Dissection of Clonal Architecture and Metabolic Properties for Clinical Interventions

MM Capelletti, O Montini, E Ruini, S Tettamanti… - International Journal of …, 2024 - mdpi.com
Genetic studies of haematological cancers have pointed out the heterogeneity of leukaemia
in its different subpopulations, with distinct mutations and characteristics, impacting the …

Vitamin C Inhibits Lipopolysaccharide-Induced Hyperinflammatory State of Chronic Myeloid Leukemia Cells through Purinergic Signaling and Autophagy

DA Pires, MAR Brandão-Rangel, A Silva-Reis… - Nutrients, 2024 - mdpi.com
Background: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm
characterized by the overproduction of white blood cells, leading to symptoms such as …

[PDF][PDF] Модуляторы нарушения гемопоэза (обзор)

НФ Салахутдинов, СС Лаев… - Химия в интересах …, 2020 - sibran.ru
Аннотация Нарушения гемопоэза (кроветворения), вызванные действием различных
факторов (гемотоксичных веществ, лекарственных и цитостатических препаратов …