Tetrazole derivatives are a prime class of heterocycles, very important to medicinal
chemistry and drug design due to not only their bioisosterism to carboxylic acid and amide …

2, 5-Diketopiperazines (2, 5-DKPs) are cyclodipeptides obtained by the condensation of two
α-amino acids. They not only abound in nature but are often produced as degradation …

Multicomponent reactions (MCRs) are fundamentally different from two‐component
reactions in several aspects. Among the MCRs, those with isocyanides have developed into …

Multicomponent reactions (MCRs) are generally defined as reactions where more than two
staring materials react to form a product, incorporating essentially all of the atoms of the …

The exploration of privileged structures in drug discovery is a rapidly emerging theme in
medicinal chemistry. These structures represent a class of molecules capable of binding to …

With the recent emergence of combinatorial chemistry and high-speed parallel synthesis for
drug discovery applications, the multi-component reaction (MCR) has seen a resurgence of …

With the emergence of high‐throughput screening in the pharmaceutical industry in the early
1990's, organic chemists were faced with a new challenge: how to prepare large collections …

The massive increase in the number of papers describing the use of polymeric supports in
organic synthesis over the past decade is a vivid demonstration of its impact in the chemical …

Benzodiazepines (BZDs), a diverse class of benzofused seven-membered N-heterocycles,
display essential pharmacological properties and play vital roles in some biochemical …

In the recent past, the design and synthesis of peptide mimics (peptidomimetics) has
received much attention. This because they have shown in many cases enhanced …