The effect of red blood cell disorders on male fertility and reproductive health

BD Naelitz, PS Khooblall, NV Parekh, SC Vij… - Nature Reviews …, 2024 - nature.com
Male infertility is defined as a failure to conceive after 12 months of unprotected intercourse
owing to suspected male reproductive factors. Non-malignant red blood cell disorders are …

[HTML][HTML] Current national and international guidelines for the management of male hypogonadism: helping clinicians to navigate variation in diagnostic criteria and …

A Al-Sharefi, R Quinton - Endocrinology and Metabolism, 2020 - synapse.koreamed.org
Male hypogonadism—rebadged by some as testosterone deficiency syndrome—is a clinical
and biochemical diagnosis of increasing worldwide interest. Organic male hypogonadism …

Effect of enhanced iron chelation therapy on glucose metabolism in patients with β‐thalassaemia major

K Farmaki, N Angelopoulos… - British journal of …, 2006 - Wiley Online Library
Recently introduced chelation regimens that combine deferoxamine (DFO) and deferiprone
have been shown to have greater efficacy in promoting iron excretion than either chelator …

[HTML][HTML] Non-neoplastic diseases of the testis

M Nistal, R Paniagua - Urologic surgical pathology, 2008 - ncbi.nlm.nih.gov
Sexual differentiation is the result of complex genetic and endocrine mechanisms that are
closely associated with the development of both the genitourinary system and the adrenal …

Genotypic and phenotypic spectra of hemojuvelin mutations in primary hemochromatosis patients: a systematic review

X Kong, L Xie, H Zhu, L Song, X Xing, W Yang… - Orphanet Journal of …, 2019 - Springer
Hereditary hemochromatosis (HH) is a genetic disorder that causes excess absorption of
iron and can lead to a variety of complications including liver cirrhosis, arthritis, abnormal …

Reduced insulin secretion in normoglycaemic patients with β‐thalassaemia major

NG Angelopoulos, A Zervas, S Livadas… - Diabetic …, 2006 - Wiley Online Library
Aims To assess insulin sensitivity and secretion in the fasting state in regularly transfused
patients with β‐thalassaemia major with normal glucose response during an oral glucose …

Early age‐of‐onset iron overload and homozygosity for the novel hemojuvelin mutation HJV R54X (exon 3; c.160A→T) in an African American male of West Indies …

RC Murugan, PL Lee, MR Kalavar… - Clinical genetics, 2008 - Wiley Online Library
An African American male of West Indies descent was diagnosed to have elevated
transferrin saturation, hyperferritinemia, severe iron deposition in hepatocytes, and hepatic …

An unexpected cause of liver cirrhosis and cardiomyopathy in a young man

R Pauwels, E Vandecasteele, D Devos… - Acta Clinica …, 2018 - Taylor & Francis
Introduction Juvenile hemochromatosis is a rare but severe form of hereditary
hemochromatosis that typically presents early in life and can be fatal if left untreated. Case …

Conséquences endocrines des hémochromatoses

J Young - La Presse Médicale, 2007 - Elsevier
Points essentiels Les 2 atteintes endocriniennes fréquentes de l'hémochromatose sont le
diabète sucré et l'hypogonadisme hypogonadotrophique. Les autres endocrinopathies sont …

Perspectives in pediatric pathology, chapter 21. Testicular pathology in heritable metabolic disease

M Nistal, R Paniagua… - Pediatric and …, 2016 - journals.sagepub.com
Inborn errors of metabolism have wide and profound effects in many or all organs, and
especially so in those with endocrine functions. The testes are greatly affected by systemic …