Summary Coronavirus disease 2019 (COVID-19) is the latest respiratory pandemic caused
by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2). Although …

The global burden of respiratory diseases is very high and still on the rise, prompting the
need for accurate models for basic and translational research. Several model systems are …

Pulmonary diseases represent four out of ten most common causes for worldwide mortality.
Thus, pulmonary infections with subsequent inflammatory responses represent a major …

Lung organoids display a tissue-specific functional phenomenon and mimic the features of
the original organ. They can reflect the properties of the cells, such as morphology, polarity …

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal degenerative lung disease of
unknown etiology. Although in its final stages it implicates, in a reactive manner, all lung cell …

Background Chronic lung disease of prematurity, called bronchopulmonary dysplasia
(BPD), lacks effective therapies, stressing the need for preclinical testing systems that reflect …

Klebsiella pneumoniae is a common cause of Gram-negative pneumonia. The spread of
antibiotic-resistant and hypervirulent strains has made treatment more challenging. This …

Respiratory diseases, ranging from minor infections to serious chronic diseases and
malignancies, negatively affect the respiratory system and are influenced by various …

Organoids are essentially an in vitro (lab-grown) three-dimensional tissue culture system
model that meticulously replicates the structure and physiology of human organs. A few of …

Background: Hantaviruses–dichotomized into New World (ie Andes virus, ANDV; Sin
Nombre virus, SNV) and Old-World viruses (ie Hantaan virus, HTNV)–are zoonotic viruses …