Among the different kinds of tumors threatening human life, lung cancer is one that is
commonly observed in both males and females. The aggressive behavior of lung cancer …

Abstract G-quadruplexes (G4s) are non-classical DNA or RNA secondary structures that
have been first observed decades ago. Over the years, these four-stranded structural motifs …

Microglia and astrocytes maintain tissue homeostasis in the nervous system. Both microglia
and astrocytes have pro-inflammatory phenotype and anti-inflammatory phenotype …

Purpose To construct a prognosis model of melanoma based on pyroptosis related genes.
Methods Melanoma RNA-sequencing data was downloaded from TCGA. First, the lnRNAs …

RNA methylation modification is a key process in epigenetics that regulates
posttranscriptional gene expression. With advances in next-generation sequencing …

The world of noncoding RNAs (ncRNAs) is composed of an enormous and growing number
of transcripts, ranging in length from tens of bases to tens of kilobases, involved in all …

Noncoding RNAs are functional transcripts that are not translated into proteins. They
represent the largest portion of the human transcriptome and have been shown to regulate …

Systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are two common
multisystem autoimmune diseases that share, among others, many clinical manifestations …

Objective Emerging studies suggest that long non-coding RNAs (lncRNAs) play crucial roles
in hepatocellular carcinoma (HCC). A rapidly increasing number of studies have shown that …

Abstract Topoisomerase IIα (TOP2A) plays an oncogenic role in multiple tumor types.
However, no pan-cancer analysis about the function and the upstream molecular …