[HTML][HTML] Molecular pathways associated with oxidative stress in diabetes mellitus

OM Ighodaro - Biomedicine & pharmacotherapy, 2018 - Elsevier
The role of oxidative stress in the occurrence and development of diabetes mellitus is both
critical and pivotal. Several molecular event cascade in different metabolic pathways such …

Reactive oxygen species (ROS) and cancer: Role of antioxidative nutraceuticals

S Prasad, SC Gupta, AK Tyagi - Cancer letters, 2017 - Elsevier
Extensive research over the past half a century indicates that reactive oxygen species (ROS)
play an important role in cancer. Although low levels of ROS can be beneficial, excessive …

Extracellular vesicle–matrix interactions

K Debnath, K Las Heras, A Rivera, S Lenzini… - Nature Reviews …, 2023 - nature.com
The extracellular matrix (ECM) harbours various signals to control cellular functions and the
materiality of tissues. Most efforts to synthetically reconstitute the matrix by biomaterial …

Antioxidant peptides, the guardian of life from oxidative stress

Y Zhu, K Wang, X Jia, C Fu, H Yu… - Medicinal Research …, 2024 - Wiley Online Library
Reactive oxygen species (ROS) are produced during oxidative metabolism in aerobic
organisms. Under normal conditions, ROS production and elimination are in a relatively …

Antioxidants and human diseases

P Rajendran, N Nandakumar, T Rengarajan… - Clinica chimica acta, 2014 - Elsevier
Oxidative stress plays a pivotal role in the development of human diseases. Reactive
oxygen species (ROS) that includes hydrogen peroxide, hyphochlorus acid, superoxide …

The antioxidant activity of polysaccharides derived from marine organisms: An overview

Q Zhong, B Wei, S Wang, S Ke, J Chen, H Zhang… - Marine drugs, 2019 - mdpi.com
Marine-derived antioxidant polysaccharides have aroused extensive attention because of
their potential nutritional and therapeutic benefits. However, the comprehensive comparison …

Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors

A Daemen, D Peterson, N Sahu… - Proceedings of the …, 2015 - National Acad Sciences
Although targeting cancer metabolism is a promising therapeutic strategy, clinical success
will depend on an accurate diagnostic identification of tumor subtypes with specific …

[HTML][HTML] Role of peroxisomes in ROS/RNS-metabolism: implications for human disease

M Fransen, M Nordgren, B Wang… - Biochimica et Biophysica …, 2012 - Elsevier
Peroxisomes are cell organelles that play a central role in lipid metabolism. At the same
time, these organelles generate reactive oxygen and nitrogen species as byproducts …

The role of oxidative stress on breast cancer development and therapy

F Hecht, CF Pessoa, LB Gentile, D Rosenthal… - Tumor biology, 2016 - Springer
Reactive oxygen species (ROS) are produced by both enzymatic and non-enzymatic
systems within eukaryotic cells and play important roles in cellular physiology and …

A review of antioxidant peptides derived from meat muscle and by-products

R Liu, L Xing, Q Fu, G Zhou, W Zhang - Antioxidants, 2016 - mdpi.com
Antioxidant peptides are gradually being accepted as food ingredients, supplemented in
functional food and nutraceuticals, to positively regulate oxidative stress in the human body …