Lipid droplet biogenesis and functions in health and disease
Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …
Lipid droplets and liver disease: from basic biology to clinical implications
NL Gluchowski, M Becuwe, TC Walther… - Nature reviews …, 2017 - nature.com
Lipid droplets are dynamic organelles that store neutral lipids during times of energy excess
and serve as an energy reservoir during deprivation. Many prevalent metabolic diseases …
and serve as an energy reservoir during deprivation. Many prevalent metabolic diseases …
Lipid droplet biogenesis
TC Walther, J Chung… - Annual review of cell and …, 2017 - annualreviews.org
Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids for energy or
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo …
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo …
Macrophage‐mediated cholesterol handling in atherosclerosis
DA Chistiakov, YV Bobryshev… - Journal of cellular and …, 2016 - Wiley Online Library
Formation of foam cells is a hallmark at the initial stages of atherosclerosis. Monocytes
attracted by pro‐inflammatory stimuli attach to the inflamed vascular endothelium and …
attracted by pro‐inflammatory stimuli attach to the inflamed vascular endothelium and …
Emerging risk biomarkers in cardiovascular diseases and disorders
RK Upadhyay - Journal of lipids, 2015 - Wiley Online Library
Present review article highlights various cardiovascular risk prediction biomarkers by
incorporating both traditional risk factors to be used as diagnostic markers and recent …
incorporating both traditional risk factors to be used as diagnostic markers and recent …
[HTML][HTML] Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis
Triacylglycerols (triglycerides)(TGs) are the major storage molecules of metabolic energy
and FAs in most living organisms. Excessive accumulation of TGs, however, is associated …
and FAs in most living organisms. Excessive accumulation of TGs, however, is associated …
Intestinal lipid absorption
J Iqbal, MM Hussain - American Journal of Physiology …, 2009 - journals.physiology.org
Our knowledge of the uptake and transport of dietary fat and fat-soluble vitamins has
advanced considerably. Researchers have identified several new mechanisms by which …
advanced considerably. Researchers have identified several new mechanisms by which …
Oxysterols: modulators of cholesterol metabolism and other processes
GJ Schroepfer Jr - Physiological reviews, 2000 - journals.physiology.org
Oxygenated derivatives of cholesterol (oxysterols) present a remarkably diverse profile of
biological activities, including effects on sphingolipid metabolism, platelet aggregation …
biological activities, including effects on sphingolipid metabolism, platelet aggregation …
Acyl-coenzyme A: cholesterol acyltransferases
The enzymes acyl-coenzyme A (CoA): cholesterol acyltransferases (ACATs) are membrane-
bound proteins that utilize long-chain fatty acyl-CoA and cholesterol as substrates to form …
bound proteins that utilize long-chain fatty acyl-CoA and cholesterol as substrates to form …
Acyl-CoA: diacylglycerol acyltransferase: molecular biology, biochemistry and biotechnology
Triacylglycerol (TG) is a storage lipid which serves as an energy reservoir and a source of
signalling molecules and substrates for membrane biogenesis. TG is essential for many …
signalling molecules and substrates for membrane biogenesis. TG is essential for many …