Exogenous factors affecting the functional integrity of male reproduction

F Tirpák, H Greifová, N Lukáč, R Stawarz, P Massányi - Life, 2021 - mdpi.com
Natural processes along with increased industrial production and the irresponsible behavior
of mankind have resulted in environmental pollution. Environmental pollutants can be …

Research progress on the role and mechanism of DNA damage repair in germ cell development

Y Wang, M Su, Y Chen, X Huang, L Ruan… - Frontiers in …, 2023 - frontiersin.org
In the complex and dynamic processes of replication, transcription, and translation of DNA
molecules, a large number of replication errors or damage can occur which lead to …

Endocrine-disrupting chemicals rapidly affect intercellular signaling in Leydig cells

A Yawer, E Sychrová, P Labohá, J Raška… - Toxicology and Applied …, 2020 - Elsevier
A decline in male fertility possibly caused by environmental contaminants, namely endocrine-
disrupting chemicals (EDCs), is a topic of public concern and scientific interest. This study …

Nonylphenol induces apoptosis through ROS/JNK signaling in a spermatogonia cell line

HJ Park, R Lee, H Yoo, K Hong, H Song - International Journal of …, 2020 - mdpi.com
Nonylphenol (NP) is an endocrine-disruptor chemical that negatively affects reproductive
health. Testes exposure to NP results in testicular structure disruption and a reduction in …

Seasonal assessment of selected trace elements in grass carp (Ctenopharyngodon idella) blood and their effects on the biochemistry and oxidative stress markers

A Kovacik, E Tvrda, M Tomka, N Revesz… - Environmental …, 2023 - Springer
Environmental pollution by anthropogenic activity is still a highly relevant global problem.
Aquatic animals are a specifically endangered group of organisms due to their continuous …

Trace elements content in semen and their interactions with sperm quality and RedOx status in freshwater fish Cyprinus carpio: A correlation study

A Kovacik, F Tirpak, M Tomka, M Miskeje… - Journal of Trace …, 2018 - Elsevier
Objective of the present study was to investigate interactions between trace elements
content and RedOx status, as well as sperm quality parameters (motility features, DNA …

Resveratrol attenuates hydrogen peroxide-induced oxidative stress in TM3 Leydig cells in vitro

H Greifová, T Jambor, K Tokárová… - … Science and Health …, 2020 - Taylor & Francis
The objective of present study was to investigate in vitro protective potential of resveratrol in
TM3 Leydig cells with induced oxidative stress using hydrogen peroxide (H2O2). Leydig …

Signaling transduction regulated by 5-hydroxytryptamine 1A receptor and orexin receptor 2 heterodimers

QQ Wang, CM Wang, BH Cheng, CQ Yang, B Bai… - Cellular …, 2019 - Elsevier
As G-protein-coupled receptors (GPCRs), 5-hydroxytryptamine 1A receptor (5-HT1AR) and
orexin receptor 2 (OX2R) regulate the levels of the cellular downstream molecules. The …

Cytotoxic effect of aminoglycoside antibiotics on the mammalian cell lines

A Kovacik, E Tvrda, T Jambor, D Fulopova… - … Science and Health …, 2020 - Taylor & Francis
Aminoglycoside antibiotics have been used for treating serious but also routine infections in
veterinary and human medicine for many years. The basic aim of this work is to evaluate the …

Evaluation of toxicity of 4-octylphenol in TM4 Sertoli cells: an in vitro study

M Zhang, HJ Park, SA Seo, HR Seo… - Toxicology Mechanisms …, 2019 - Taylor & Francis
The reproductive toxicity of 4-octylphenol (4-OP) has been studied in animals such as
mouse and fish. In humans, the exposure of sperm to 4-OP has been shown to decrease …