Anti-depressant properties of crocin molecules in saffron

SA Siddiqui, A Ali Redha, ER Snoeck, S Singh… - Molecules, 2022 - mdpi.com
Saffron is a valued herb, obtained from the stigmas of the C. sativus Linn (Iridaceae), with
therapeutic effects. It has been described in pharmacopoeias to be variously acting …

Phytotherapic use of the Crocus sativus L. (Saffron) and its potential applications: A brief overview

S Leone, L Recinella, A Chiavaroli… - Phytotherapy …, 2018 - Wiley Online Library
Crocus sativus L.(Saffron) has long been known for multiple target therapeutic uses. The
plant metabolism is well investigated and the main metabolites related to saffron …

Effect of saffron supplementation on symptoms of depression and anxiety: a systematic review and meta-analysis

W Marx, M Lane, T Rocks, A Ruusunen… - Nutrition …, 2019 - academic.oup.com
Abstract Context Saffron (Crocus sativus L.) has gained interest as a potential treatment in
psychiatry. Objective This systematic review and meta-analysis sought to investigate the …

[HTML][HTML] Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence

SF Omidkhoda, H Hosseinzadeh - Iranian Journal of Basic Medical …, 2022 - ncbi.nlm.nih.gov
Saffron, the stigmas of Crocus sativus L., has been mentioned extensively in the traditional
reference texts as a herbal medicine. Many clinical trials have been conducted on this …

The efficacy of saffron in the treatment of mild to moderate depression: a meta-analysis

B Tóth, P Hegyi, T Lantos, Z Szakacs, B Kerémi… - Planta …, 2019 - thieme-connect.com
Herbal products, especially Hypericum perforatum extracts, have been widely used as first-
line treatments for mild to moderate depression. Recently, several randomized, controlled …

The genus Crocus L.: A review of ethnobotanical uses, phytochemistry and pharmacology

L Mohtashami, MS Amiri, M Ramezani… - Industrial Crops and …, 2021 - Elsevier
Crocus L. is a genus of perennial plants in the family Iridaceae. Numerous research
regarding healing effects of Crocus spp. on human diseases are being published worldwide …

Redox modulation of stress resilience by Crocus sativus L. for potential neuroprotective and anti-neuroinflammatory applications in brain disorders: From molecular …

M Scuto, S Modafferi, F Rampulla, V Zimbone… - Mechanisms of Ageing …, 2022 - Elsevier
Recent evidence demonstrates that Crocus sativus L.(saffron) counteracts oxidative stress,
mitochondrial dysfunction and neuroinflammation, closely linked to initiation and …

[HTML][HTML] Turmeric: potential health benefits

K Singletary - Nutrition Today, 2020 - journals.lww.com
For centuries, Curcuma longa (turmeric) was used as a spice in Asian cuisine and as a
medicinal herb for treatment of inflammation, pain, wound healing, and digestive disorders …

Safety and efficacy of saffron (Crocus sativus L.) for treating mild to moderate depression: a systematic review and meta-analysis

L Dai, L Chen, W Wang - The Journal of nervous and mental …, 2020 - journals.lww.com
Background Herbal remedies are becoming increasingly popular for the treatment of
depression. Recently, accumulating evidences reveal a positive effect of saffron (Crocus …

Circulating Human Serum Metabolites Derived from the Intake of a Saffron Extract (Safr'InsideTM) Protect Neurons from Oxidative Stress: Consideration for …

F Wauquier, L Boutin-Wittrant, L Pourtau, D Gaudout… - Nutrients, 2022 - mdpi.com
Increases in oxidative stress have been reported to play a central role in the vulnerability to
depression, and antidepressant drugs may reduce increased oxidative stress in patients …