[HTML][HTML] Characterising live cell behaviour: Traditional label-free and quantitative phase imaging approaches

R Kasprowicz, R Suman, P O'Toole - … journal of biochemistry & cell biology, 2017 - Elsevier
Label-free imaging uses inherent contrast mechanisms within cells to create image contrast
without introducing dyes/labels, which may confound results. Quantitative phase imaging is …

Classification of M1/M2-polarized human macrophages by label-free hyperspectral reflectance confocal microscopy and multivariate analysis

FR Bertani, P Mozetic, M Fioramonti, M Iuliani… - Scientific reports, 2017 - nature.com
The possibility of detecting and classifying living cells in a label-free and non-invasive
manner holds significant theranostic potential. In this work, Hyperspectral Imaging (HSI) has …

The CellPhe toolkit for cell phenotyping using time-lapse imaging and pattern recognition

L Wiggins, A Lord, KL Murphy, SE Lacy… - Nature …, 2023 - nature.com
With phenotypic heterogeneity in whole cell populations widely recognised, the demand for
quantitative and temporal analysis approaches to characterise single cell morphology and …

Voltage‐dependent activation of Rac1 by Nav1.5 channels promotes cell migration

M Yang, AD James, R Suman… - Journal of cellular …, 2020 - Wiley Online Library
Ion channels can regulate the plasma membrane potential (Vm) and cell migration as a
result of altered ion flux. However, the mechanism by which Vm regulates motility remains …

Wave packet in the phase problem in optics and ptychography

NL Popov, IA Artyukov, AV Vinogradov… - Physics …, 2020 - iopscience.iop.org
At present, ptychography seems to be the most natural and efficient method for approaching
the diffraction-limited optical resolution. The general setup of a ptychoscope does not …

Nanospermidine in combination with nanofenretinide induces cell death in neuroblastoma cell lines

P Lodeserto, M Rossi, P Blasi, G Farruggia, I Orienti - Pharmaceutics, 2022 - mdpi.com
A new strategy to cause cell death in tumors might be the increase of intracellular
polyamines at concentrations above their physiological values to trigger the production of …

[HTML][HTML] Naxitamab activity in neuroblastoma cells is enhanced by nanofenretinide and nanospermidine

L Galassi, M Rossi, P Lodeserto, M Lenzi, F Borsetti… - Pharmaceutics, 2023 - mdpi.com
Neuroblastoma cells highly express the disialoganglioside GD2, a tumor-associated
carbohydrate antigen, which is also expressed in neurons, skin melanocytes, and peripheral …

[HTML][HTML] Neuroprotective activity of ursodeoxycholic acid in CHMP2BIntron5 models of frontotemporal dementia

RJH West, C Ugbode, L Fort-Aznar, ST Sweeney - Neurobiology of disease, 2020 - Elsevier
Frontotemporal dementia (FTD) is one of the most prevalent forms of early-onset dementia. It
represents part of the FTD-Amyotrophic Lateral Sclerosis (ALS) spectrum, a continuum of …

Quadriwave lateral shearing interferometric microscopy with wideband sensitivity enhancement for quantitative phase imaging in real time

T Ling, J Jiang, R Zhang, Y Yang - Scientific reports, 2017 - nature.com
Real-time quantitative phase imaging has tremendous potential in investigating live
biological specimens in vitro. Here we report on a wideband sensitivity-enhanced …

Label-free morpho-molecular phenotyping of living cancer cells by combined Raman spectroscopy and phase tomography

A Bresci, KJ Kobayashi-Kirschvink, G Cerullo… - Communications …, 2024 - nature.com
Accurate, rapid and non-invasive cancer cell phenotyping is a pressing concern across the
life sciences, as standard immuno-chemical imaging and omics require extended sample …