Serology as a tool to assess infectious disease landscapes and guide public health policy
AH Haselbeck, J Im, K Prifti, F Marks, M Holm… - Pathogens, 2022 - mdpi.com
Understanding the local burden and epidemiology of infectious diseases is crucial to guide
public health policy and prioritize interventions. Typically, infectious disease surveillance …
public health policy and prioritize interventions. Typically, infectious disease surveillance …
Germline-encoded amino acid–binding motifs drive immunodominant public antibody responses
EL Shrock, RT Timms, T Kula, EL Mena, AP West Jr… - Science, 2023 - science.org
Despite the vast diversity of the antibody repertoire, infected individuals often mount
antibody responses to precisely the same epitopes within antigens. The immunological …
antibody responses to precisely the same epitopes within antigens. The immunological …
The insider: impact of the gut microbiota on cancer immunity and response to therapies in multiple myeloma
A Brevi, LL Cogrossi, M Lorenzoni, B Mattorre… - Frontiers in …, 2022 - frontiersin.org
The human microbiota is a unique set of microorganisms colonizing the human body and
evolving within it from the very beginning. Acting as an insider, the microbiota provides …
evolving within it from the very beginning. Acting as an insider, the microbiota provides …
The systemic anti-microbiota IgG repertoire can identify gut bacteria that translocate across gut barrier surfaces
Unique gut microbiota compositions have been associated with inflammatory diseases, but
identifying gut bacterial functions linked to immune activation in humans remains …
identifying gut bacterial functions linked to immune activation in humans remains …
Systemic antibody responses against human microbiota flagellins are overrepresented in chronic fatigue syndrome patients
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease with
an unclear etiology and pathogenesis. Both an involvement of the immune system and gut …
an unclear etiology and pathogenesis. Both an involvement of the immune system and gut …
Phage-display immunoprecipitation sequencing of the antibody epitope repertoire in inflammatory bowel disease reveals distinct antibody signatures
Inflammatory bowel diseases (IBDs), eg, Crohn's disease (CD) and ulcerative colitis (UC),
are chronic immune-mediated inflammatory diseases. A comprehensive overview of an IBD …
are chronic immune-mediated inflammatory diseases. A comprehensive overview of an IBD …
Autoantibody discovery across monogenic, acquired, and COVID-19-associated autoimmunity with scalable PhIP-seq
SE Vazquez, SA Mann, A Bodansky, AF Kung… - Elife, 2022 - elifesciences.org
Phage immunoprecipitation sequencing (PhIP-seq) allows for unbiased, proteome-wide
autoantibody discovery across a variety of disease settings, with identification of disease …
autoantibody discovery across a variety of disease settings, with identification of disease …
Phage ImmunoPrecipitation Sequencing (PhIP-Seq): the promise of high throughput serology
Simple Summary Determining the exposure or infection history of a person to a multitude of
viruses is not an easy task. Typically, antibody tests detect antibodies against proteins …
viruses is not an easy task. Typically, antibody tests detect antibodies against proteins …
Microecosystem of yak rumen on the Qinghai‐Tibetan Plateau is stable and is unaffected by soil or grass microbiota
Q Fan, K Xie, X Cui, G Zhang, H Zheng… - Environmental …, 2022 - Wiley Online Library
The rumen of livestock grazing on the Qinghai‐Tibetan Plateau (QTP) acts as a transfer
station for the circulation of soil, grass, faecal mineral elements and nutrients. Whether the …
station for the circulation of soil, grass, faecal mineral elements and nutrients. Whether the …
Intergenerational protective anti-gut commensal immunoglobulin G originates in early life
B Rusconi, AK Bard, R McDonough… - Proceedings of the …, 2024 - National Acad Sciences
Maternal immunoglobulins of the class G (IgGs) protect offspring from enteric infection, but
when, where, and how these antibodies are physiologically generated and confer protection …
when, where, and how these antibodies are physiologically generated and confer protection …