[HTML][HTML] Liquid-liquid phase separation as a common organizing principle of intracellular space and biomembranes providing dynamic adaptive responses
SV Nesterov, NS Ilyinsky, VN Uversky - Biochimica et Biophysica Acta (BBA …, 2021 - Elsevier
This work is devoted to the phenomenon of liquid-liquid phase separation (LLPS), which has
come to be recognized as fundamental organizing principle of living cells. We distinguish …
come to be recognized as fundamental organizing principle of living cells. We distinguish …
Intrinsically disordered proteins play diverse roles in cell signaling
Signaling pathways allow cells to detect and respond to a wide variety of chemical (eg Ca2+
or chemokine proteins) and physical stimuli (eg, sheer stress, light). Together, these …
or chemokine proteins) and physical stimuli (eg, sheer stress, light). Together, these …
Genomic survey of TCP transcription factors in plants: Phylogenomics, evolution and their biology
H Zhou, D Hwarari, H Ma, H Xu, L Yang, Y Luo - Frontiers in genetics, 2022 - frontiersin.org
The TEOSINTE BRANCHED1 (TBI1), CYCLOIDEA (CYC), and PROLIFERATING CELL
NUCLEAR ANTIGEN FACTORS (PCF1 and PCF2) proteins truncated as TCP transcription …
NUCLEAR ANTIGEN FACTORS (PCF1 and PCF2) proteins truncated as TCP transcription …
Weak interactions in higher-order chromatin organization
OL Kantidze, SV Razin - Nucleic acids research, 2020 - academic.oup.com
The detailed principles of the hierarchical folding of eukaryotic chromosomes have been
revealed during the last two decades. Along with structures composing three-dimensional …
revealed during the last two decades. Along with structures composing three-dimensional …
mRNA-miRNA analyses reveal the involvement of CsbHLH1 and miR1446a in the regulation of caffeine biosynthesis in Camellia sinensis
Q Jin, Z Wang, D Sandhu, L Chen, C Shao… - Horticulture …, 2024 - academic.oup.com
Caffeine, a primary flavor component in tea, has been the subject of intense research. With
the goal of shedding light on the complex regulatory processes governing caffeine …
the goal of shedding light on the complex regulatory processes governing caffeine …
The role of liquid–liquid phase separation in the compartmentalization of cell nucleus and spatial genome organization
SV Razin, AA Gavrilov - Biochemistry (Moscow), 2020 - Springer
Functional compartmentalization of the cell nucleus plays an important role in the regulation
of genome activity by providing accumulation of enzymes and auxiliary factors in the …
of genome activity by providing accumulation of enzymes and auxiliary factors in the …
Lighting up Nobel Prize-winning studies with protein intrinsic disorder
L Piersimoni, M Abd el Malek, T Bhatia… - Cellular and Molecular …, 2022 - Springer
Intrinsically disordered proteins and regions (IDPs and IDRs) and their importance in biology
are becoming increasingly recognized in biology, biochemistry, molecular biology and …
are becoming increasingly recognized in biology, biochemistry, molecular biology and …
Corneal fibrosis abrogation by a localized AAV-mediated inhibitor of differentiation 3 (Id3) gene therapy in rabbit eyes in vivo
Previously we found that inhibitor of differentiation 3 (Id3) gene, a transcriptional repressor,
efficiently inhibits corneal keratocyte differentiation to myofibroblasts in vitro. This study …
efficiently inhibits corneal keratocyte differentiation to myofibroblasts in vitro. This study …
Tumor suppressor protein p53 expressed in yeast can remain diffuse, form a prion, or form unstable liquid-like droplets
SK Park, S Park, C Pentek, SW Liebman - Iscience, 2021 - cell.com
Mutations in the p53 tumor suppressor are frequent causes of cancer. Because p53
aggregates appear in some tumor cells, it has been suggested that p53 could also cause …
aggregates appear in some tumor cells, it has been suggested that p53 could also cause …
Intrinsically disordered regions in the transcription factor MYC: MAX modulate DNA binding via intramolecular interactions
The basic helix–loop–helix leucine zipper (bHLH-LZ) transcription factor (TF) MYC is in
large part an intrinsically disordered oncoprotein. In complex with its obligate …
large part an intrinsically disordered oncoprotein. In complex with its obligate …