Brain function relies on the ability of neurons to communicate with each other. Interneuronal
communication primarily takes place at synapses, where information from one neuron is …

Myopia is far beyond its inconvenience and represents a true, highly prevalent, sight-
threatening ocular condition, especially in Asia. Without adequate interventions, the current …

By its action on rhodopsin, light triggers the well-known visual transduction cascade, but can
also induce cell damage and death through phototoxic mechanisms–a comprehensive …

Innate social behaviours emerge from neuronal circuits that interpret sensory information on
the basis of an individual's own genotype, sex and experience. The regulated aggregation …

As a more complete picture of the clinical phenotype of Parkinson's disease emerges, non-
motor symptoms have become increasingly studied. Prominent among these non-motor …

Visual signals in the vertebrate retina are shaped by feedback and feedforward inhibition in
two synaptic layers. In one, horizontal cells establish fundamental center-surround receptive …

Electrical synaptic transmission through gap junctions underlies direct and rapid neuronal
communication in the CNS. The diversity of functional roles that electrical synapses have is …

Lateral interactions in the outer retina, particularly negative feedback from horizontal cells to
cones and direct feed-forward input from horizontal cells to bipolar cells, play a number of …

Synaptic interactions to extract information about wavelength, and thus color, begin in the
vertebrate retina with three classes of light-sensitive cells: rod photoreceptors at low light …

Dopamine is a key neuromodulator in the retina and brain that supports motor, cognitive,
and visual function. Here, we developed a mouse model on a C57 background in which …