The bioactive sphingolipid metabolites ceramide and sphingosine-1-phosphate (S1P) are a
recent addition to the lipids accumulated in obesity and have emerged as important …

Ceramide is a core molecule of sphingolipid metabolism that causes selective insulin
resistance and dyslipidemia. Research on its involvement in cardiovascular diseases has …

Lipids represent a valuable target for metabolomic studies since altered lipid metabolism is
known to drive the pathological changes in cardiovascular disease (CVD). Metabolomic …

Sphingolipids are a structural component of the cell membrane, derived from sphingosine,
an amino alcohol. Its sphingoid base undergoes various types of enzymatic transformations …

Although the serum lipidome is markedly affected by COVID-19, two unresolved issues
remain: how the severity of the disease affects the level and the composition of serum lipids …

The medical community recognizes sex-related differences in pathophysiology and
cardiovascular disease outcomes (CVD), culminating with heart failure. In general, pre …

Cardiovascular diseases are the leading cause of mortality worldwide and this has largely
been driven by the increase in metabolic disease in recent decades. Metabolic disease …

Background Metabolomics has immense research value in coronary artery disease and has
drawn increasing attention over the past decades. Many articles have been published in this …

Aims The aim of this scoping review is to evaluate the current biomarkers used in the
assessment of adverse cardiac remodelling in people with diabetes mellitus (DM) and in the …

BACKGROUND: Dysregulated metabolism of bioactive sphingolipids, including ceramides
and sphingosine-1-phosphate, has been implicated in cardiovascular disease, although the …