Cannabis extracts in oil are becoming increasingly available, and, during the last years,
there has been growing public and scientific interest about therapeutic properties of these …

Epilepsy is a common and debilitating neurological disorder, and approximately one-third of
affected individuals have ongoing seizures despite appropriate trials of two anti-seizure …

OBJECTIVE Medically refractory epilepsy remains a therapeutic challenge when resective
surgery is not a practical option and indirect neurostimulation efficacy may be limited. In …

Objectives This study aimed to elucidate the effects of Gentiopicroside (Gent) on
epileptogenesis and underlying mechanisms. Methods The status epilepticus (SE) model …

Introduction Drug-resistant epilepsy (DRE) significantly affects the development and quality
of life of children and young adults. Objective To describe the effectiveness and safety of …

Saikosaponin-a (SSa) exhibits antiepileptic effects. However, its poor water solubility and
inability to pass through the blood–brain barrier greatly limit its clinical development and …

Materials and Methods: The present clinical trial was conducted as a prospective 12-month,
open-label, case-controlled interventional study. Thirty-six ASD children who were newly …

This paper intended to study the mechanism and active ingredients of ACB anti-epilepsy.
The antiepileptic activity of ACB validated in PTZ kindled rats, ACB could increase the …

We present a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method
for quantifying fenfluramine (FFA), its active metabolite norfenfluramine (norFFA), and …

Objective Corticosteroids and adrenocorticotropic hormone (ACTH) are the therapy of
choice to treat infantile spasms. However, systematic studies about their use in other types of …