[HTML][HTML] From pyroptosis, apoptosis and necroptosis to PANoptosis: A mechanistic compendium of programmed cell death pathways

Y Wang, TD Kanneganti - Computational and structural biotechnology …, 2021 - Elsevier
Pyroptosis, apoptosis and necroptosis are the most genetically well-defined programmed
cell death (PCD) pathways, and they are intricately involved in both homeostasis and …

New insights into the evasion of host innate immunity by Mycobacterium tuberculosis

Q Chai, L Wang, CH Liu, B Ge - Cellular & molecular immunology, 2020 - nature.com
Mycobacterium tuberculosis (Mtb) is an extremely successful intracellular pathogen that
causes tuberculosis (TB), which remains the leading infectious cause of human death. The …

A major role for ferroptosis in Mycobacterium tuberculosis–induced cell death and tissue necrosis

EP Amaral, DL Costa, S Namasivayam… - Journal of Experimental …, 2019 - rupress.org
Necrotic cell death during Mycobacterium tuberculosis (Mtb) infection is considered host
detrimental since it facilitates mycobacterial spread. Ferroptosis is a type of regulated …

When ferroptosis meets pathogenic infections

J Gao, Q Wang, YD Tang, J Zhai, W Hu, C Zheng - Trends in microbiology, 2023 - cell.com
Apoptosis, necrosis, or autophagy are diverse types of regulated cell death (RCD),
recognized as the strategies that host cells use to defend against pathogens such as …

Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity

P Meier, AJ Legrand, D Adam, J Silke - Nature Reviews Cancer, 2024 - nature.com
Most metastatic cancers remain incurable due to the emergence of apoptosis-resistant
clones, fuelled by intratumour heterogeneity and tumour evolution. To improve treatment …

Mitochondrial quality control in cardiac microvascular ischemia-reperfusion injury: new insights into the mechanisms and therapeutic potentials

J Wang, S Toan, H Zhou - Pharmacological Research, 2020 - Elsevier
Thrombolytic therapy and revascularization strategies create a complete recanalization of
the occluded epicardial coronary artery in patients with myocardial infarction (MI). However …

Flipping the dogma–phosphatidylserine in non-apoptotic cell death

I Shlomovitz, M Speir, M Gerlic - Cell Communication and Signaling, 2019 - Springer
The exposure of phosphatidylserine (PS) on the outer plasma membrane has long been
considered a unique feature of apoptotic cells. Together with other “eat me” signals, it …

NAD+ depletion triggers macrophage necroptosis, a cell death pathway exploited by Mycobacterium tuberculosis

D Pajuelo, N Gonzalez-Juarbe, U Tak, J Sun… - Cell reports, 2018 - cell.com
Mycobacterium tuberculosis (Mtb) kills infected macrophages by inhibiting apoptosis and
promoting necrosis. The tuberculosis necrotizing toxin (TNT) is a secreted nicotinamide …

[HTML][HTML] Macrophage and neutrophil death programs differentially confer resistance to tuberculosis

MD Stutz, CC Allison, S Ojaimi, SP Preston… - Immunity, 2021 - cell.com
Apoptosis can potently defend against intracellular pathogens by directly killing microbes
and eliminating their replicative niche. However, the reported ability of Mycobacterium …

[HTML][HTML] Type I interferon signaling mediates Mycobacterium tuberculosis–induced macrophage death

L Zhang, X Jiang, D Pfau, Y Ling… - Journal of Experimental …, 2021 - rupress.org
Macrophages help defend the host against Mycobacterium tuberculosis (Mtb), the major
cause of tuberculosis (TB). Once phagocytized, Mtb resists killing by macrophages …