The role of thiols in antioxidant systems
The sulfur biochemistry of the thiol group endows cysteines with a number of highly
specialized and unique features that enable them to serve a variety of different functions in …
specialized and unique features that enable them to serve a variety of different functions in …
[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …
Redox regulation by reversible protein S-thiolation in bacteria
VV Loi, M Rossius, H Antelmann - Frontiers in microbiology, 2015 - frontiersin.org
Low molecular weight (LMW) thiols function as thiol-redox buffers to maintain the reduced
state of the cytoplasm. The best studied LMW thiol is the tripeptide glutathione (GSH) …
state of the cytoplasm. The best studied LMW thiol is the tripeptide glutathione (GSH) …
Thiol-based redox switches in prokaryotes
M Hillion, H Antelmann - Biological chemistry, 2015 - degruyter.com
Bacteria encounter reactive oxygen species (ROS) as a consequence of the aerobic life or
as an oxidative burst of activated neutrophils during infections. In addition, bacteria are …
as an oxidative burst of activated neutrophils during infections. In addition, bacteria are …
Cysteine and resistance to oxidative stress: implications for virulence and antibiotic resistance
Reactive oxygen species (ROS), including the superoxide radical anion (O 2•–), hydrogen
peroxide (H 2 O 2), and the hydroxyl radical (• HO), are inherent components of bacterial …
peroxide (H 2 O 2), and the hydroxyl radical (• HO), are inherent components of bacterial …
[HTML][HTML] Peroxiredoxins wear many hats: Factors that fashion their peroxide sensing personalities
Peroxiredoxins (Prdxs) sense and assess peroxide levels, and signal through protein
interactions. Understanding the role of the multiple structural and post-translational …
interactions. Understanding the role of the multiple structural and post-translational …
One-and two-electron oxidation of thiols: mechanisms, kinetics and biological fates
M Trujillo, B Alvarez, R Radi - Free radical research, 2016 - Taylor & Francis
The oxidation of biothiols participates not only in the defense against oxidative damage but
also in enzymatic catalytic mechanisms and signal transduction processes. Thiols are …
also in enzymatic catalytic mechanisms and signal transduction processes. Thiols are …
The Role of Bacillithiol in Gram-Positive Firmicutes
P Chandrangsu, VV Loi, H Antelmann… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Since the discovery and structural characterization of bacillithiol (BSH), the
biochemical functions of BSH-biosynthesis enzymes (BshA/B/C) and BSH-dependent …
biochemical functions of BSH-biosynthesis enzymes (BshA/B/C) and BSH-dependent …
[HTML][HTML] Redox regulation by reversible protein S-thiolation in Gram-positive bacteria
M Imber, AJ Pietrzyk-Brzezinska, H Antelmann - Redox biology, 2019 - Elsevier
Low molecular weight (LMW) thiols play an important role as thiol-cofactors for many
enzymes and are crucial to maintain the reduced state of the cytoplasm. Most Gram-negative …
enzymes and are crucial to maintain the reduced state of the cytoplasm. Most Gram-negative …
Protein CoAlation and antioxidant function of coenzyme A in prokaryotic cells
Y Tsuchiya, A Zhyvoloup, J Baković… - Biochemical …, 2018 - portlandpress.com
In all living organisms, coenzyme A (CoA) is an essential cofactor with a unique design
allowing it to function as an acyl group carrier and a carbonyl-activating group in diverse …
allowing it to function as an acyl group carrier and a carbonyl-activating group in diverse …