CD69 is a membrane‐bound, type II C‐lectin receptor. It is a classical early marker of
lymphocyte activation due to its rapid appearance on the surface of the plasma membrane …

One of the earliest cell surface antigens expressed by T cells following activation is CD69,
which is detectable within one h of ligation of the T cell receptor/CD3 complex. Once …

Tissue-resident memory CD8+ T cells (TRM) constitute a noncirculating memory T cell
subset that provides early protection against reinfection. However, how TRM arise from …

▪ Abstract Natural killer cells are likely to play an important role in the host defenses because
they kill virally infected or tumor cells but spare normal self-cells. The molecular mechanism …

Lymphocyte egress from lymph nodes requires the G-protein-coupled sphingosine 1-
phosphate receptor-1 (S1P 1). The activation antigen CD69 associates with and inhibits the …

CD69 is an early leukocyte activation molecule expressed at sites of chronic inflammation.
The precise role of CD69 in immunity has not been elucidated owing to the absence of a …

In rodents, the NKR-P1 family of glycoproteins are preferentially expressed on NK cells and
have been implicated in NK cell function. In this study, we describe the characterization and …

CD69 was initially described as being restricted to recently activated lymphoid cells, but is
now known to be expressed on the surface of all hematopoietically derived leukocytes …

Fas ligand (FasL) triggers apoptosis during cytotoxicity mediated by cytotoxic T lymphocytes
and during immune downregulation 1. The ability of T cells and natural killer cells to trigger …

CD69 is a differentiation antigen expressed shortly after activation on T lymphocytes and
other cells of haematopoietic origin, including natural killer (NK) cells. The function of CD69 …