Dendritic cells (DCs) are a heterogeneous group of antigen-presenting innate immune cells
that regulate adaptive immunity, including against cancer. Therefore, understanding the …

Plasmacytoid dendritic cells (pDCs) represent a unique cell type within the innate immune
system. Their defining property is the recognition of pathogen-derived nucleic acids through …

Conventional dendritic cells (cDCs) include functionally and phenotypically diverse
populations, such as cDC1s and cDC2s. The latter population has been variously …

Regulation of high-density loci harboring genes with different cell-specificities remains a
puzzle. Here we investigate a locus that evolved through gene duplication and contains …

Cytokines produced in association with tumors can impair antitumor immune responses by
reducing the abundance of type 1 conventional dendritic cells (cDC1), but the mechanism …

Antigen cognate dendritic cell (DC)-T cell synaptic interactions drive activation of T cells and
instruct DCs. Upon receiving CD4+ T cell help, post-synaptic DCs (psDCs) are licensed to …

Our understanding of allergic contact dermatitis mechanisms has progressed over the past
decade. Innate immune cells that are involved in the pathogenesis of allergic contact …

Dendritic cells (DCs) are sentinel immune cells that form a critical bridge linking the innate
and adaptive immune systems. Extensive research addressing the cellular origin and …

Dendritic cells (DCs) are innate immune cells that detect and process environmental signals
and communicate them with T cells to bridge innate and adaptive immunity. Immune signals …

Monocytes can differentiate into macrophages (Mo-Macs) or dendritic cells (Mo-DCs). The
cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) induces the …