Drug-induced osteoporosis is a significant health problem and many physicians are
unaware that many commonly prescribed medications contribute to significant bone loss …

Within the past 2 decades, organ transplantation has become established as effective
therapy for endstage renal, hepatic, cardiac, and pulmonary disease. Regimens to prevent …

SUMMARY Receptors for 1, 25 (OH) 2vitaminD3 are found in most immune cells and
important immunological effects have been described in vitro, reflected by its capacity to …

Cardiac transplantation is associated with increased prevalence and incidence of fracture,
and rapid bone loss has been reported during the first posttransplant year. To define further …

Bone loss leading to osteoporosis is common after the menopause and in the elderly but
uncommon in normal young adults without predisposing factors. The risk factors usually …

Bone loss in long-term renal transplantation: Histopathology and densitometry analysis.
Background There is little information of the spectrum and factors implicated in the bone loss …

We describe a constellation of bone diseases characterized by the common feature of acute,
rapid, and severe bone loss accompanied by dramatic fracture rates. These disorders are …

Cardiac transplantation is associated with severe bone loss caused by glucocorticoids,
immunosuppressive treatment, and other factors. Treatment protocols for the prevention of …

The immunosuppressant agent cyclosporin A (CsA) induces a high turnover osteopenic
state, while the effect on bone of the antimetabolite azathioprine, a drug often used in …

Immunosuppressant therapy is associated with osteoporosis both clinically, post‐
transplantation, and experimentally. In rats, cyclosporin A (CsA) and FK506 induce a state of …