Metallo-β-lactamases: a last frontier for β-lactams?

G Cornaglia, H Giamarellou… - The Lancet infectious …, 2011 - thelancet.com
Metallo-β-lactamases are resistance determinants of increasing clinical relevance in Gram-
negative bacteria. Because of their broad range, potent carbapenemase activity and …

[HTML][HTML] Novel gene cassettes and integrons in antibiotic-resistant bacteria isolated from urban wastewaters

A Moura, C Pereira, I Henriques, A Correia - Research in microbiology, 2012 - Elsevier
In this study, the occurrence and diversity of integrons were evaluated in 697 isolates
belonging to Enterobacteriaceae and Aeromonas spp. isolated from urban wastewaters …

Tackling Carbapenem Resistance and the Imperative for One Health Strategies—Insights from the Portuguese Perspective

I Mó, GJ da Silva - Antibiotics, 2024 - mdpi.com
Carbapenemases, a class of enzymes specialized in the hydrolysis of carbapenems,
represent a significant threat to global public health. These enzymes are classified into …

Analysis of a long-term outbreak of XDR Pseudomonas aeruginosa: a molecular epidemiological study

M Willmann, D Bezdan, L Zapata… - Journal of …, 2015 - academic.oup.com
Objectives Here we report on a long-term outbreak from 2009 to 2012 with an XDR
Pseudomonas aeruginosa on two wards at a university hospital in southern Germany …

Characterization of pKP-M1144, a novel ColE1-like plasmid encoding IMP-8, GES-5, and BEL-1 β-lactamases, from a Klebsiella pneumoniae sequence type 252 …

CC Papagiannitsis, M Dolejska… - Antimicrobial agents …, 2015 - Am Soc Microbiol
ABSTRACT IMP-8 metallo-β-lactamase was identified in Klebsiella pneumoniae sequence
type 252 (ST252), isolated in a Portuguese hospital in 2009. bla IMP-8 was the first gene …

VIM-1, VIM-34, and IMP-8 carbapenemase-producing Escherichia coli strains recovered from a Portuguese river

N Kieffer, L Poirel, LJ Bessa… - Antimicrobial agents …, 2016 - Am Soc Microbiol
The emergence of acquired carbapenemases is currently one of the most serious public
health threats worldwide. These enzymes confer resistance to almost all β-lactams …

Emergence of IMP-8-Producing Comamonas thiooxydans Causing Urinary Tract Infection in China

X Guo, Q Wang, H Xu, X He, L Guo, S Liu… - Frontiers in …, 2021 - frontiersin.org
The emergence of carbapenem resistance (CR) caused by hydrolytic enzymes called
carbapenemases has become a major concern worldwide. So far, CR genes have been …

Clinical cases of VIM-producing Pseudomonas mendocina from two burned patients

M Almuzara, SD Montaña, ME Carulla, G Sly… - 2018 - ri.conicet.gov.ar
Since its first description in 1970 by Palleroni et al. from water and soil samples collected in
the province of Mendoza in Argentina [1], few cases of human infection by Pseudomonas …

Emergence of Citrobacter freundii carrying IMP‐8 metallo‐β‐lactamase in Germany

S Peter, C Wolz, M Kaase, M Marschal… - New Microbes and …, 2014 - Wiley Online Library
Metallo‐β‐lactamases (MBL s) in Enterobacteriaceae are an increasing problem worldwide.
This report describes the isolation of C itrobacter freundii carrying IMP‐8 MBL from three …

Escherichia coli with blaIMP-8 in Singapore

TH Koh, D Cao, NWS Tee, JWP Teo - Antimicrobial agents and …, 2014 - Am Soc Microbiol
2006. The carbapenem MICs by Etest (bioMérieux SA, Marcy l'Etoile, France) were
ertapenem at 2 g/l, meropenem at 4 g/l, and imipenem at 32 g/l. A modified Hodge test was …