In this review, we summarize current knowledge of perhaps one of the most intriguing
phenomena in cell biology: the mitochondrial permeability transition pore (mPTP). This …

Mitochondrial permeability transition, as the consequence of opening of a mitochondrial
permeability transition pore (mPTP), is a cellular catastrophe. Initiating bioenergetic collapse …

Mitochondrial permeability transition pore (PTP), a (patho) physiological phenomenon
discovered over 40 years ago, is still not completely understood. PTP activation results in a …

Cyclophilin D (CypD) is a key regulator of mitochondrial permeability transition pore (mPTP)
opening. This pathophysiological phenomenon is associated with the development of …

Bioenergetic failure often features programmed cell death involved in some severe
pathologies. When the cell is fated to die, the inner mitochondrial membrane becomes …

As the heart is an energy-demanding organ, impaired cardiac energy metabolism and
mitochondrial function have been inexorably linked to cardiac dysfunction. There is a …

The relevance of mitochondrial DNA (mtDNA) mutations in cancer process is still unknown.
Since the mutagenesis of mitochondrial genome in mammals is not possible yet, we have …

It is now firmly established that an important event in the formation of reperfusion injury of the
heart is the opening of mitochondrial permeability transition pores (mPTPs), which changes …

The mitochondrial permeability transition pore (PTP) is now recognized as playing a key role
in a wide variety of human diseases whose common pathology may be based in …

There is no comprehensive method for differentiating between fresh and frozen-thawed fish
fillets. This is an ongoing problem, particularly in relation to regulations. In this study, we …