The development of multicellular organisms is controlled by highly dynamic molecular and
cellular processes organized in spatially restricted patterns. Recent advances in …

The cellular cytoskeleton self-organizes by specific monomer–monomer interactions
resulting in the polymerization of filaments. While we have long thought about the role of …

Tissue flow during morphogenesis is commonly driven by local constriction of cell cortices,
which is caused by the activation of actomyosin contractility. This can lead to long-range …

Cells receive enormous amounts of information from their environment. How they act on this
information—by migrating, expressing genes, or relaying signals to other cells—comprises …

Many eukaryotes form multinucleated cells during their development. Some cells persist as
such during their lifetime, others choose to cleave each nucleus individually using a …

During morphogenesis, changes in the shapes of individual cells are harnessed to mold an
entire tissue. These changes in cell shapes require the coupled remodeling of the plasma …

Apicobasal cell polarity loss is a founding event in epithelial–mesenchymal transition and
epithelial tumorigenesis, yet how pathological polarity loss links to plasticity remains largely …

Critical periods are temporally-restricted, early-life windows when sensory experience
remodels synaptic connectivity to optimize environmental input. In the Drosophila juvenile …

Distinct patterns of actomyosin contractility are often associated with particular epithelial
tissue shape changes during development. For example, a planar-polarized pattern of …

Actomyosin‐mediated apical constriction drives a wide range of morphogenetic processes.
Activation of myosin‐II initiates pulsatile cycles of apical constrictions followed by either …