Strategies to develop polymeric microneedles for controlled drug release

BZ Chen, YT He, ZQ Zhao, YH Feng, L Liang… - Advanced Drug Delivery …, 2023 - Elsevier
The remarkable appeal of microneedle controlled-release systems has captivated both the
academic community and pharmaceutical industry due to their great potential for achieving …

[HTML][HTML] Design and fabrication of customizable microneedles enabled by 3D printing for biomedical applications

JM Loh, YJL Lim, JT Tay, HM Cheng, HL Tey, K Liang - Bioactive Materials, 2024 - Elsevier
Microneedles (MNs) is an emerging technology that employs needles ranging from 10 to
1000 μm in height, as a minimally invasive technique for various procedures such as …

Intestine-inspired wrinkled MXene microneedle dressings for smart wound management

H Lu, W Shao, B Gao, S Zheng, B He - Acta Biomaterialia, 2023 - Elsevier
Composite MXene-based materials are prone to crack propagation, thus limiting their tensile
properties. Numerous efforts have been devoted to removing material constraints and …

Layer-by-layer microneedle-mediated rhEGF transdermal delivery for enhanced wound epidermal regeneration and angiogenesis

R Yuan, N Yang, Y Huang, W Li, Y Zeng… - … Applied Materials & …, 2023 - ACS Publications
Appropriate treatments for acute traumas tend to avoid hemorrhages, vascular damage, and
infections. However, in the homeostasis-imbalanced wound microenvironment, currently …

Recent advances in multifunctional microneedle patches for wound healing and health monitoring

P Pan, Q Liu, L Wang, C Wang, L Hu… - Advanced …, 2023 - Wiley Online Library
Benefiting from the advantages of minimal invasiveness, painlessness, and ease to use,
microneedle patches (MPs) have been extensively studied in the biomedical field through a …

A Glucose-Responsive Glucagon-Micelle for the Prevention of Hypoglycemia

D Vinciguerra, PS Rajalakshmi, J Yang… - ACS Central …, 2024 - ACS Publications
While glucose-responsive insulin delivery systems are in widespread clinical use to treat
insulin insufficiency, the on-demand supplementation of glucagon for acute hypoglycemia …

3D printing of biologics—what has been accomplished to date?

A Lu, RO Williams III, M Maniruzzaman - Drug Discovery Today, 2024 - Elsevier
Three-dimensional (3D) printing is a promising approach for the stabilization and delivery of
non-living biologics. This versatile tool builds complex structures and customized …

Advances of Smart Stimulus‐Responsive Microneedles in Cancer Treatment

H Chu, J Xue, Y Yang, H Zheng, D Luo, Z Li - Small Methods, 2024 - Wiley Online Library
Microneedles (MNs) have emerged as a highly promising technology for delivering drugs
via the skin. They provide several benefits, including high drug bioavailability, non …

[HTML][HTML] A perspective on transformative bioprinting

CK Chua, J An, S Fan, X Zhang, L Ouyang… - … Journal of Bioprinting, 2024 - accscience.com
Our understanding of bioprinting originated from tissue engineering and 3D printing. Over
the last two decades, 3D printing has been serving tissue engineering to fulfill its goal of …

Direct 3D printing of triple-responsive nanocomposite hydrogel microneedles for controllable drug delivery

X Zhou, H Liu, Z Yu, H Yu, D Meng, L Zhu… - Journal of Colloid and …, 2024 - Elsevier
Hydrogel microneedle patches have emerged as promising platforms for painless, minimally
invasive, safe, and portable transdermal drug administration. However, the conventional …