Human aging is a gradual and adaptive process characterized by a decrease in the
homeostatic response, leading to biochemical and molecular changes that are driven by …

Ferroptosis is an emerging and novel type of iron-dependent programmed cell death which
is mainly caused by the excessive deposition of free intracellular iron in the brain cells. This …

Abstract Background Radix Astragali Mongolici, as a traditional Chinese medicine, is widely
used in the treatment of qi deficiency, viral or bacterial infection, inflammation and cancer …

Abstract Peroxiredoxin 6 (Prdx6) is a multifunctional enzyme, a unique member of the
peroxiredoxin family, with an important role in antioxidant defense. Moreover, it has also …

Abstract Peroxiredoxin 6 (Prdx6) is a bifunctional enzyme with multi-substrate peroxidase
and phospholipase activities that is involved in cell redox homeostasis and regulates …

The uptake and digestion of host hemoglobin by malaria parasites during blood-stage
growth leads to significant oxidative damage of membrane lipids. Repair of lipid …

Significance: Peroxiredoxins (Prdxs) with a single peroxidative cysteine (CP) in a conserved
motif PXXX (T/S) XXCP within its thioredoxin fold, have been classified as the peroxiredoxin …

Abstract Background Andrographolide (Andro) is a diterpenoid derived from Andrographis
paniculate, which has anti-inflammatory, antibacterial, antiviral and hepatoprotective …

Abstract Peroxiredoxin 6 (Prdx6), the ubiquitously expressed enzyme belonging to the family
of peroxidases, namely, peroxiredoxins, exhibits a unique feature of functional …

Peroxiredoxin 6 (Prdx6), a unique 1-Cys member of the peroxiredoxin family, exhibits
peroxidase activity, phospholipase activity, and lysophosphatidylcholine acyltransferase …