The impact of the human thalamus on brain-wide information processing
The thalamus is a small, bilateral structure in the diencephalon that integrates signals from
many areas of the CNS. This critical anatomical position allows the thalamus to influence …
many areas of the CNS. This critical anatomical position allows the thalamus to influence …
Clinical electroencephalography for anesthesiologists: part I: background and basic signatures
The widely used electroencephalogram-based indices for depth-of-anesthesia monitoring
assume that the same index value defines the same level of unconsciousness for all …
assume that the same index value defines the same level of unconsciousness for all …
Sleep deprivation impairs molecular clearance from the human brain
It remains an enigma why human beings spend one-third of their life asleep. Experimental
data suggest that sleep is required for clearance of waste products from brain metabolism …
data suggest that sleep is required for clearance of waste products from brain metabolism …
Deep brain stimulation of the thalamus restores signatures of consciousness in a nonhuman primate model
Loss of consciousness is associated with the disruption of long-range thalamocortical and
corticocortical brain communication. We tested the hypothesis that deep brain stimulation …
corticocortical brain communication. We tested the hypothesis that deep brain stimulation …
Effective connectivity changes in LSD-induced altered states of consciousness in humans
Psychedelics exert unique effects on human consciousness. The thalamic filter model
suggests that core effects of psychedelics may result from gating deficits, based on a …
suggests that core effects of psychedelics may result from gating deficits, based on a …
Unique spatiotemporal fMRI dynamics in the awake mouse brain
Human imaging studies have shown that spontaneous brain activity exhibits stereotypic
spatiotemporal reorganization in awake, conscious conditions with respect to minimally …
spatiotemporal reorganization in awake, conscious conditions with respect to minimally …
Pain and the triple network model
Acute pain is a physiological response that causes an unpleasant sensory and emotional
experience in the presence of actual or potential tissue injury. Anatomically and …
experience in the presence of actual or potential tissue injury. Anatomically and …
Towards a comprehensive understanding of anesthetic mechanisms of action: a decade of discovery
Significant progress has been made in the 21st century towards a comprehensive
understanding of the mechanisms of action of general anesthetics, coincident with progress …
understanding of the mechanisms of action of general anesthetics, coincident with progress …
In vivo mapping of pharmacologically induced functional reorganization onto the human brain's neurotransmitter landscape
To understand how pharmacological interventions can exert their powerful effects on brain
function, we need to understand how they engage the brain's rich neurotransmitter …
function, we need to understand how they engage the brain's rich neurotransmitter …
Anesthesia with Dexmedetomidine and Low-dose Isoflurane Increases Solute Transport via the Glymphatic Pathway in Rat Brain When Compared with High-dose …
H Benveniste, H Lee, F Ding, Q Sun, E Al-Bizri… - …, 2017 - pubs.asahq.org
Background The glymphatic pathway transports cerebrospinal fluid through the brain,
thereby facilitating waste removal. A unique aspect of this pathway is that its function …
thereby facilitating waste removal. A unique aspect of this pathway is that its function …