Vitamin D in neurological diseases

D Plantone, G Primiano, C Manco, S Locci… - International journal of …, 2022 - mdpi.com
Vitamin D may have multiple effects on the nervous system and its deficiency can represent
a possible risk factor for the development of many neurological diseases. Recent studies are …

Vitamin D supplementation in multiple sclerosis: a critical analysis of potentials and threats

J Feige, T Moser, L Bieler, K Schwenker, L Hauer… - Nutrients, 2020 - mdpi.com
Multiple sclerosis (MS) is a chronic inflammatory demyelinating and neurodegenerative
disease of the central nervous system (CNS). In recent years, vitamin D has gained …

Full spectrum of vitamin D immunomodulation in multiple sclerosis: Mechanisms and therapeutic implications

M Galoppin, S Kari, S Soldati, A Pal… - Brain …, 2022 - academic.oup.com
Vitamin D deficiency has been associated with the risk of multiple sclerosis, disease activity
and progression. Results from in vitro experiments, animal models and analysis of human …

Mendelian randomization study updates the effect of 25-hydroxyvitamin D levels on the risk of multiple sclerosis

R Wang - Journal of translational medicine, 2022 - Springer
Background Observational studies and previous Mendelian randomization (MR) studies
have shown that genetically low 25-hydroxyvitamin D (25OHD) levels are associated with a …

Vitamin D and neurodegenerative diseases

W Wang, Y Li, X Meng - Heliyon, 2023 - cell.com
Neurodegenerative diseases, featured by progressive loss of structure or function of
neurons, are considered incurable at present. Movement disorders like tremor and postural …

Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity

P Ostkamp, A Salmen, B Pignolet… - Proceedings of the …, 2021 - National Acad Sciences
Multiple sclerosis (MS) disease risk is associated with reduced sun-exposure. This study
assessed the relationship between measures of sun exposure (vitamin D [vitD], latitude) and …

Effects of vitamin D and body mass index on disease risk and relapse hazard in multiple sclerosis: a Mendelian randomization study

M Vandebergh, B Dubois, A Goris - Neurology: Neuroimmunology …, 2022 - AAN Enterprises
Background and Objectives Decreased vitamin D levels and obesity are associated with an
increased risk for multiple sclerosis (MS). However, whether they also affect the disease …

A brief review of the effects of vitamin D on multiple sclerosis

A Miclea, M Bagnoud, A Chan, R Hoepner - Frontiers in immunology, 2020 - frontiersin.org
Multiple sclerosis (MS) is characterized as an autoimmune disease affecting the central
nervous system. It is one of the most common neurological disorders in young adults. Over …

Associations of serum short-chain fatty acids with circulating immune cells and serum biomarkers in patients with multiple sclerosis

S Trend, J Leffler, AP Jones, L Cha, S Gorman… - Scientific Reports, 2021 - nature.com
Altered composition of gut bacteria and changes to the production of their bioactive
metabolites, the short-chain fatty acids (SCFAs), have been implicated in the development of …

Using personalized prognosis in the treatment of relapsing multiple sclerosis: A practical guide

B Van Wijmeersch, HP Hartung, P Vermersch… - Frontiers in …, 2022 - frontiersin.org
The clinical course of multiple sclerosis (MS) is highly variable among patients, thus creating
important challenges for the neurologist to appropriately treat and monitor patient progress …