There are numerous investigated factors that limit brain cancer treatment efficacy such as
ability of prescribed therapy to cross the blood-brain barrier (BBB), tumor specific delivery of …

Nonviral nanoparticles have emerged as an attractive alternative to viral vectors for gene
therapy applications, utilizing a range of lipid‐based, polymeric, and inorganic materials …

Clinical translation of polymer‐based nanocarriers for systemic delivery of RNA has been
limited due to poor colloidal stability in the blood stream and intracellular delivery of the RNA …

Pediatric brain tumors represent the most common types of childhood cancer and novel
diagnostic and therapeutic solutions are urgently needed. The gold standard treatment …

Brain tumors are the leading cause of morbidity and mortality related to cancer in children,
where high-grade glioma harbor the worst prognosis. It has become obvious that pediatric …

Magnetic nanoparticles (MNPs) are a promising drug delivery system to treat brain diseases,
as the particle transport trajectory can be manipulated by an external magnetic field …

Low uptake efficiency in vivo as well as systemic toxicities of nucleic‐acid nanovehicles
substantially retard the clinical translation of gene therapy. Targeted gene delivery to …

Glioma is one of the most serious central nervous system diseases, with high mortality and
poor prognosis. Despite the continuous development of existing treatment methods, the …

Генотерапевтические лекарственные препараты (ГТЛП) в настоящее время активно
разрабатываются в различных странах, в том числе в Российской Федерации. Однако …

This chapter revises the application of UV-Vis spectrophotometry and spectrofluorimetry in
bioanalysis. It focuses on techniques that rely on the absorption and emission of light for the …