The distribution of gut microbiota varies according to age (childhood, puberty, pregnancy,
menopause, and old age) and sex. Gut microbiota are known to contribute to gastrointestinal …

The release and absorption profile of an oral medication is influenced by the
physicochemical properties of the drug and its formulation, as well as by the anatomy and …

Abstract Treatment with therapy targeting BRAF and MEK (BRAF/MEK) has revolutionized
care in melanoma and other cancers; however, therapeutic resistance is common and …

Sex differences in immunity are well described in the literature and thought to be mainly
driven by sex hormones and sex-linked immune response genes. The gastrointestinal tract …

Background Gonadal steroid hormones have been suggested as the underlying mechanism
responsible for the sexual dimorphism observed in metabolic diseases. Animal studies have …

Sex is a critical factor in the diagnosis and development of a number of mental health
disorders including autism, schizophrenia, depression, anxiety, Parkinson's disease …

Strong evidence suggests that early-life exposures to suboptimal environmental factors,
including those in utero, influence our long-term metabolic health. This has been termed …

BACKGROUND: Gut microbiota have been implicated in atherosclerotic disease, but their
relation with subclinical coronary atherosclerosis is unclear. This study aimed to identify …

Results: A total of 10,468 records were screened with 13 studies included in this review. In
healthy women, higher estrogen levels were found to be associated with a higher …

The gut is colonized by many commensal microorganisms, and the diversity and metabolic
patterns of microorganisms profoundly influence the intestinal health. These microbial …