Genetic analyses from ancient DNA

S Pääbo, H Poinar, D Serre… - Annu. Rev …, 2004 - annualreviews.org
▪ Abstract About 20 years ago, DNA sequences were separately described from the quagga
(a type of zebra) and an ancient Egyptian individual. What made these DNA sequences …

African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping

MC Campbell, SA Tishkoff - Annu. Rev. Genomics Hum. Genet., 2008 - annualreviews.org
Comparative studies of ethnically diverse human populations, particularly in Africa, are
important for reconstructing human evolutionary history and for understanding the genetic …

[图书][B] Who we are and how we got here: Ancient DNA and the new science of the human past

D Reich - 2018 - books.google.com
The past few years have witnessed a revolution in our ability to obtain DNA from ancient
humans. This important new data has added to our knowledge from archaeology and …

A draft sequence of the Neandertal genome

RE Green, J Krause, AW Briggs, T Maricic, U Stenzel… - science, 2010 - science.org
Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of
Europe and western Asia before disappearing 30,000 years ago. We present a draft …

Genetic history of an archaic hominin group from Denisova Cave in Siberia

D Reich, RE Green, M Kircher, J Krause, N Patterson… - Nature, 2010 - nature.com
Using DNA extracted from a finger bone found in Denisova Cave in southern Siberia, we
have sequenced the genome of an archaic hominin to about 1.9-fold coverage. This …

Testing for ancient admixture between closely related populations

EY Durand, N Patterson, D Reich… - Molecular biology and …, 2011 - academic.oup.com
One enduring question in evolutionary biology is the extent of archaic admixture in the
genomes of present-day populations. In this paper, we present a test for ancient admixture …

Temporal patterns of nucleotide misincorporations and DNA fragmentation in ancient DNA

S Sawyer, J Krause, K Guschanski, V Savolainen… - PloS one, 2012 - journals.plos.org
DNA that survives in museum specimens, bones and other tissues recovered by
archaeologists is invariably fragmented and chemically modified. The extent to which such …

The strength of selection against Neanderthal introgression

I Juric, S Aeschbacher, G Coop - PLoS genetics, 2016 - journals.plos.org
Hybridization between humans and Neanderthals has resulted in a low level of Neanderthal
ancestry scattered across the genomes of many modern-day humans. After hybridization, on …

The date of interbreeding between Neandertals and modern humans

S Sankararaman, N Patterson, H Li, S Pääbo, D Reich - 2012 - journals.plos.org
Comparisons of DNA sequences between Neandertals and present-day humans have
shown that Neandertals share more genetic variants with non-Africans than with Africans …

Uganda genome resource enables insights into population history and genomic discovery in Africa

D Gurdasani, T Carstensen, S Fatumo, G Chen… - Cell, 2019 - cell.com
Genomic studies in African populations provide unique opportunities to understand disease
etiology, human diversity, and population history. In the largest study of its kind, comprising …