Patterns are ubiquitous in living systems and underlie the dynamic organization of cells,
tissues, and embryos. Mathematical frameworks have been devised to account for the self …

Actin dynamics in cell motility, division, and phagocytosis is regulated by complex factors
with multiple feedback loops, often leading to emergent dynamic patterns in the form of …

During cell migration and polarization, numerous signal transduction and cytoskeletal
components self-organize to generate localized protrusions. Although biochemical and …

Despite the ability of peripheral nerves to spontaneously regenerate after injury, recovery is
generally very poor. The neurotrophins have emerged as an important modulator of axon …

Severe peripheral nerve injuries often result in permanent loss of function of the affected
limb. Current treatments are limited by their efficacy in supporting nerve regeneration and …

Glioma is the most prevalent brain tumor, presenting with limited treatment options, while
patients with malignant glioma and glioblastoma (GBM) have poor prognoses. The physical …

Despite the prevalence of superresolution (SR) microscopy, quantitative live-cell SR
imaging that maintains the completeness of delicate structures and the linearity of …

Osteoclasts form a specialized cell–matrix adhesion structure, known as the “sealing zone”,
during bone resorption. The sealing zone is a dynamic actin-rich structure that defines the …

Summary The Ras/PI3K/extracellular signal-regulated kinases (ERK) signaling network
plays fundamental roles in cell growth, survival, and migration and is frequently activated in …

Many biological events, such as the propagation of nerve impulses, the synchronized cell
cycles of early embryogenesis, and collective cell migration, must be coordinated with …