Elective versus therapeutic neck dissection in node-negative oral cancer: evidence from five randomized controlled trials

ZH Ren, JL Xu, B Li, TF Fan, T Ji, CP Zhang - Oral oncology, 2015 - Elsevier
The aim of this study was to compare the outcomes of elective neck dissection (END) with
that of a more conservative approach comprising of observation plus therapeutic neck …

Elective neck dissection in T1/T2 oral squamous cell carcinoma with N0 neck: essential or not? A systematic review and meta-analysis

SA Ibrahim, ANA Ahmed, HA Elsersy… - European Archives of Oto …, 2020 - Springer
Introduction Oral squamous cell carcinoma (SCC) is characterized by a high risk of cervical
lymph node metastasis with a high incidence of occult metastasis. A strong debate is still …

Management of the neck in squamous cell carcinoma of the oral cavity and oropharynx: ASCO clinical practice guideline

SA Koyfman, N Ismaila, D Crook, A D'Cruz… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE The aim of the current work is to provide evidence-based recommendations to
practicing physicians and others on the management of the neck in patients with squamous …

Trends in oral cavity cancer incidence, mortality, survival and treatment in the Netherlands

BAC van Dijk, MT Brands, SME Geurts… - … journal of cancer, 2016 - Wiley Online Library
Information on epidemiology is essential to evaluate care for the growing group of oral
cancer patients. We investigated trends in incidence, mortality and relative survival rates for …

Management of N0 neck in early oral squamous cell carcinoma: a systematic review and meta‐analysis

C Massey, A Dharmarajan, RR Bannuru… - The …, 2019 - Wiley Online Library
Objective The role of elective neck dissection (END) in patients with stage I (T1N0) and II
(T2N0) squamous cell carcinoma of the oral cavity remains a controversial topic. We …

Clinico-pathological prognosticators in oral squamous cell carcinoma: An update

B Majumdar, S Patil, SC Sarode… - … Research in Oral …, 2017 - journals.sagepub.com
Despite diagnostic and therapeutic advancements, mortality and morbidity rates in the
patients diagnosed with oral cancer remain static. Hence, an understanding of the factors …

Predictive significance of tumor depth and budding for late lymph node metastases in patients with clinical N0 early oral tongue carcinoma

Y Hori, A Kubota, T Yokose, M Furukawa… - Head and neck …, 2017 - Springer
In clinical N0 early oral tongue carcinoma, treatment of occult lymph node metastasis is
controversial. The purpose of this study was to assess the histopathological risk factors for …

Elective neck dissection improves the survival of patients with T2N0M0 oral squamous cell carcinoma: a study of the SEER database

A Wushou, F Yibulayin, L Sheng, Y Luo, Z Yang - BMC cancer, 2021 - Springer
Background Treatment of clinical N0 neck tumours is controversial in early-stage oral
squamous cell carcinoma (OSCC), possibly because T1N0M0 and T2N0M0 merge together …

Association between pathological invasion patterns and late lymph node metastases in patients with surgically treated clinical No early oral tongue carcinoma

Y Hori, A Kubota, T Yokose, M Furukawa… - Head & …, 2020 - Wiley Online Library
Background This study evaluated the combination of tumor budding and depth (BD model)
and worst pattern of invasion (WPOI) as histopathological prognostic factors in clinical N0 …

Oral cavity squamous cell carcinoma: factors related to occult lymph node metastasis

AF d'Alessandro, FR Pinto, CS Lin… - Brazilian journal of …, 2015 - SciELO Brasil
INTRODUCTION: Elective neck dissection is recommended in cases of oral cavity
squamous cell carcinoma without lymph node metastasis because of the risk of occult …