Background and objective Chronic neuropathic pain (NP) is a chronic pain condition that
severely impacts a patient's life. Pain management has proved to be inefficient due to a lack …

Background Chronic pain poses a multifaceted and prevalent challenge that significantly
affects an individual's quality of life. Sensory mechanisms, behavioural components …

Chronic neuropathic pain arises from changes in the somatosensory nervous system and
can lead to disability and intense physical and emotional suffering. Recognized as a painful …

Optogenetics is a novel biotechnology widely used to precisely manipulate a specific
peripheral sensory neuron or neural circuit. However, the use of optogenetics to assess the …

Cognitive behavioral therapy (CBT) is believed to be an effective treatment for chronic pain
due to its association with cognitive and emotional factors. Nevertheless, there is a paucity of …

Thirty-six chronic neuropathic pain patients (8 men and 28 women) of Mexican nationality
with a mean age of 44±13.98 were recruited for EEG signal recording in eyes open and …

Chronic painful knee osteoarthritis (OA) is a disabling physical health condition. Alterations
in brain responses to arthritic changes in the knee may explain persistent pain. This study …

While neural oscillations play a critical role in sensory perception, it remains unclear how
these rhythms function under conditions of neuropathic allodynia. Recent studies …

This work aimed to test the effect of 7-day exposure of rats to multifunctional enkephalin
analogs LYS739 and LYS744 at doses of 3 mg/kg and 10 mg/kg on the protein composition …

Purpose Chronic pain (CP) acceptance is a major factor in determining the well-being of
patients with chronic pain. The chronic pain acceptance questionnaire (CPAQ) was …