[HTML][HTML] Proteome profile of peripheral myelin in healthy mice and in a neuropathy model

SB Siems, O Jahn, MA Eichel, N Kannaiyan, LMN Wu… - Elife, 2020 - elifesciences.org
Proteome and transcriptome analyses aim at comprehending the molecular profiles of the
brain, its cell-types and subcellular compartments including myelin. Despite the relevance of …

[HTML][HTML] The transcription factor Stat-1 is essential for Schwann cell differentiation, myelination and myelin sheath regeneration

J Xu, B Zhang, J Cai, Q Peng, J Hu, P Askar… - Molecular …, 2023 - Springer
Background Myelin sheath is a crucial accessory to the functional nerve-fiber unit, its
disruption or loss can lead to axonal degeneration and subsequent neurodegenerative …

Transcriptome analysis of Schwann cells at various stages of myelination implicates chromatin regulator Sin3A in control of myelination identity

B Zhang, W Su, J Hu, J Xu, P Askar, S Bao, S Zhou… - Neuroscience …, 2022 - Springer
Enhancing remyelination after injury is of utmost importance for optimizing the recovery of
nerve function. While the formation of myelin by Schwann cells (SCs) is critical for the …

Compositional and structural characterization of dorsal root ganglion neurons and co-cultured Schwann cells by confocal Raman microspectral imaging

J Li - Vibrational Spectroscopy, 2024 - Elsevier
Confocal Raman microspectral imaging (CRMI) is a versatile non-invasive technique that
allows in vitro cell imaging without any chemical fixation, fluorescent markers or other …

[HTML][HTML] The Etv1/Er81 transcription factor coordinates myelination-related genes to regulate Schwann cell differentiation and myelination

P Askar, J Xu, J Hu, J Shangguan, H Sun… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Axonal myelination is critical for the functioning of vertebrate nervous system.
Myelin sheath malformation or degeneration can cause a variety of neurological diseases …

Characterization of sciatic nerve myelin sheath during development in C57BL/6 mice

Y Chen, T Shang, J Sun, Y Ji, L Gong… - European Journal of …, 2024 - Wiley Online Library
Myelin sheath plays important roles in information conduction and nerve injury repair in the
peripheral nerve system (PNS). Enhancing comprehension of the structure and components …

[HTML][HTML] Neuronal–Glial Interaction in a Triple-Transgenic Mouse Model of Alzheimer's Disease: Gene Ontology and Lithium Pathways

NKR Rocha, R Themoteo, H Brentani… - Frontiers in …, 2020 - frontiersin.org
Neuronal-glial interactions are critical for brain homeostasis, and disruption of this process
may lead to excessive glial activation and inadequate pro-inflammatory responses …

An electroceutical approach enhances myelination via upregulation of lipid biosynthesis in the dorsal root ganglion

A Intisar, WH Kim, HY Shin, MY Kim, YS Kim… - …, 2022 - iopscience.iop.org
As the myelin sheath is crucial for neuronal saltatory conduction, loss of myelin in the
peripheral nervous system (PNS) leads to demyelinating neuropathies causing muscular …

[HTML][HTML] Genome expression profiling predicts the molecular mechanism of peripheral myelination

X Wu - International journal of molecular medicine, 2018 - spandidos-publications.com
The present study aimed to explore the molecular mechanism of myelination in the
peripheral nervous system (PNS) based on genome expression profiles. Microarray data …

Influence of lithium in neuron-glia interaction in hippocampal neurons: preliminary study

NKR Rocha, OV Forlenza, DS Kerr, H Brentani… - Revista de …, 2018 - revistas.usp.br
Recently, special attention has been given to the possible neuroprotective effects of lithium,
especially by the discovery of its regulatory effects on pro and anti-apoptotic proteins …