A detailed understanding of the processes controlling adipogenesis is instrumental in the
fight against the obesity epidemic. Adipogenesis is controlled by a transcriptional cascade …

Abstract Cell division cycle 25 (CDC25) phosphatases regulate key transitions between cell
cycle phases during normal cell division, and in the event of DNA damage they are key …

Cell cycle regulation is performed by cyclins and cyclin dependent kinases (CDKs).
Recently, it has become clear that reactive oxygen species (ROS) influence the presence …

The CDC25 phosphatases are key regulators of normal cell division and the cell's response
to DNA damage. Earlier studies suggested non-overlapping roles for each isoform during a …

The Cdc25 phosphatases function as key regulators of the cell cycle during normal
eukaryotic cell division and as mediators of the checkpoint response in cells with DNA …

It is well known that G1 to S phase transition is tightly regulated by the expression and
phosphorylation of a number of well‐characterized cyclins, cyclin‐dependent kinases and …

Cdc25 phosphatases are essential for the activation of mitotic cyclin–Cdks, but the precise
roles of the three mammalian isoforms (A, B, and C) are unclear. Using RNA interference to …

Protein kinase B (PKB/Akt) is an important modulator of insulin signaling, cell proliferation,
and survival. Using small interfering RNA duplexes in nontransformed mammalian cells, we …

Here, we assessed and compared the anticancer efficacy and associated mechanisms of
silymarin and silibinin in human prostate cancer (PCA) PC3 cells; silymarin is comprised of …

Crocetin, a carotenoid compound derived from saffron, has long been used as a traditional
ancient medicine against different human diseases including cancer. The aim of the series …