Quiescent cancer cells—a potential therapeutic target to overcome tumor resistance and relapse
E Lindell, L Zhong, X Zhang - International Journal of Molecular Sciences, 2023 - mdpi.com
Quiescent cancer cells (QCCs) are nonproliferating cells arrested in the G0 phase,
characterized by ki67low and p27high. QCCs avoid most chemotherapies, and some …
characterized by ki67low and p27high. QCCs avoid most chemotherapies, and some …
The roles of ERIANIN in tumor and innate immunity and its' perspectives in immunotherapy
Z Yang, R Liu, M Qiu, H Mei, J Hao, T Song… - Frontiers in …, 2023 - frontiersin.org
Traditional Chinese medicine has been used in China for thousands of years. In 2022, the
14th Five-Year Plan for the Development of Traditional Chinese Medicine was released …
14th Five-Year Plan for the Development of Traditional Chinese Medicine was released …
Cuproptosis enhances docetaxel chemosensitivity by inhibiting autophagy via the DLAT/mTOR pathway in prostate cancer
H Wen, C Qu, Z Wang, H Gao, W Liu… - The FASEB …, 2023 - Wiley Online Library
Cuproptosis, a newly discovered programmed cell death induced by copper ions, is
associated with the progression and drug resistance of various tumors. Docetaxel plays a …
associated with the progression and drug resistance of various tumors. Docetaxel plays a …
Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer
Background Pancreatic cancer (PAC), a malignancy that is fatal and commonly diagnosed at
a late stage. Despite considerable advancements in cancer treatment, the survival rate of …
a late stage. Despite considerable advancements in cancer treatment, the survival rate of …
Reactive oxygen species nanoamplifiers with multi-enzymatic activities for enhanced tumor therapy
S Zhao, K Lai, Z Gao, X Ye, J Mou, S Yang, H Wu - Nanoscale, 2023 - pubs.rsc.org
The ingenious combination of nano-enzymes with multi-enzyme activities and therapeutic
drugs that can promote reactive oxygen species (ROS) production in cancer cells will …
drugs that can promote reactive oxygen species (ROS) production in cancer cells will …
[HTML][HTML] Inhibition of autophagy induced by tetrandrine promotes the accumulation of reactive oxygen species and sensitizes efficacy of tetrandrine in pancreatic …
Y Wang, T Xu, H Wang, G Xia, X Huang - Cancer Cell International, 2024 - ncbi.nlm.nih.gov
Pancreatic cancer, characterized by its poor prognosis, exhibits a marked resistance to
conventional chemotherapy and immunotherapy, underscoring the urgent need for more …
conventional chemotherapy and immunotherapy, underscoring the urgent need for more …
A specific super-enhancer actuated by berberine regulates EGFR-mediated RAS–RAF1–MEK1/2–ERK1/2 pathway to induce nasopharyngeal carcinoma autophagy
Y Wu, Q Jia, Q Tang, L Chen, H Deng, Y He… - Cellular & Molecular …, 2024 - Springer
Nasopharyngeal carcinoma (NPC), primarily found in the southern region of China, is a
malignant tumor known for its highly metastatic characteristics. The high mortality rates …
malignant tumor known for its highly metastatic characteristics. The high mortality rates …
[HTML][HTML] Unveiling cancer dormancy: intrinsic mechanisms and extrinsic forces
Tumor cells disseminate in various distant organs at early stages of cancer progression.
These disseminated tumor cells (DTCs) can stay dormant/quiescent without causing patient …
These disseminated tumor cells (DTCs) can stay dormant/quiescent without causing patient …
Targeting Unique Features of Quiescent Cancer Stem Cells to Overcome Resistance and Recurrence in Cancer Therapy: A Review
Quiescent cancer stem cells (QCSC) are non-proliferating cells that survive in the G0 phase
and have low ki-67 expression and high p27 expression. QCSCs have the ability to evade …
and have low ki-67 expression and high p27 expression. QCSCs have the ability to evade …
Saikosaponin-d Mediates FOXG1 to Reverse Docetaxel Resistance in Prostate Cancer through Oxidative Phosphorylation
J Meng, B Yang, C Shu, S Jiang - Mutation Research-Fundamental and …, 2024 - Elsevier
Abstract Background Prostate cancer (PCa), a prevalent malignancy worldwide, is frequently
identified in advanced stages due to the absence of distinctive early symptoms, thereby …
identified in advanced stages due to the absence of distinctive early symptoms, thereby …