Introduction 3. Adult mesenchymal stem cells in cartilage repair 4. Articular cartilage: from
structure to function 5. Chondrogenesis is regulated by interplay between numerous intra …

During chondrogenesis, complex intracellular signalling pathways regulate an intricate
series of events including condensation of chondroprogenitor cells and nodule formation …

This book covers the latest research and advancements related to articular cartilage in
biology, development, pathology, clinical applications and tissue engineering. The authors …

Treatments for primary and metastatic melanomas are rarely effective. Even therapeutics
such as retinoic acid (RA) that are successfully used to treat several other forms of cancer …

Biomechanical stimuli play important roles in the formation of articular cartilage during early
foetal life, and optimal mechanical load is a crucial regulatory factor of adult chondrocyte …

Osteoarthritis (OA); the most common form of degenerative joint disease, is associated with
variations in pro-inflammatory growth factor levels, inflammation and hypocellularity …

Cartilage repair by mesenchymal stem cells (MSCs) often occurs in diseased joints in which
the inflamed microenvironment impairs chondrogenic maturation and causes neocartilage …

Musculoskeletal conditions are a major burden on individuals, healthcare systems, and
social care systems throughout the world, with indirect costs having a predominant …

Chondrogenesis is known to be regulated by calcium-dependent signalling pathways in
which temporal aspects of calcium homeostasis are of key importance. We aimed to better …

Skeletal development is a complex process regulated by multifactorial signaling cascades
that govern proper tissue specific cell differentiation and matrix production. The influence of …