CRISPR‐Cas‐based detection for food safety problems: Current status, challenges, and opportunities

Y Li, S Man, S Ye, G Liu, L Ma - Comprehensive Reviews in …, 2022 - Wiley Online Library
Food safety is one of the biggest public issues occurring around the world. Microbiological,
chemical, and physical hazards can lead to food safety issues, which may occur at all stages …

CRISPR‐Cas biochemistry and CRISPR‐based molecular diagnostics

Z Weng, Z You, J Yang, N Mohammad… - Angewandte Chemie …, 2023 - Wiley Online Library
Polymerase chain reaction (PCR)‐based nucleic acid testing has played a critical role in
disease diagnostics, pathogen surveillance, and many more. However, this method requires …

A CRISPR/Cas12a-empowered surface plasmon resonance platform for rapid and specific diagnosis of the Omicron variant of SARS-CoV-2

Z Chen, J Li, T Li, T Fan, C Meng, C Li… - National Science …, 2022 - academic.oup.com
The outbreak of the COVID-19 pandemic was partially due to the challenge of identifying
asymptomatic and presymptomatic carriers of the virus, and thus highlights a strong …

A highly sensitive CRISPR‐empowered surface plasmon resonance sensor for diagnosis of inherited diseases with femtomolar‐level real‐time quantification

F Zheng, Z Chen, J Li, R Wu, B Zhang, G Nie… - Advanced …, 2022 - Wiley Online Library
The clustered regularly interspaced short palindromic repeats (CRISPR) molecular system
has emerged as a promising technology for the detection of nucleic acids. Herein, the …

[HTML][HTML] Programmable CRISPR-Cas9 microneedle patch for long-term capture and real-time monitoring of universal cell-free DNA

B Yang, J Kong, X Fang - Nature communications, 2022 - nature.com
Recent advances in biointerfaces have led to the development of wearable devices that can
provide insights into personal health. As wearable modules, microneedles can extract …

[HTML][HTML] CRISPR-Cas12a-empowered electrochemical biosensor for rapid and ultrasensitive detection of SARS-CoV-2 delta variant

C Wu, Z Chen, C Li, Y Hao, Y Tang, Y Yuan, L Chai… - Nano-Micro Letters, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gold standard method …

An ultrasensitive CRISPR/Cas12a based electrochemical biosensor for Listeria monocytogenes detection

F Li, Q Ye, M Chen, B Zhou, J Zhang, R Pang… - Biosensors and …, 2021 - Elsevier
Listeria monocytogenes is an important foodborne pathogen that can cause listeriosis with
high patient mortality. Accordingly, it is necessary to develop a L. monocytogenes detection …

Advances in CRISPR-based SERS detection of food contaminants: a review

M Hajikhani, Y Zhang, X Gao, M Lin - Trends in Food Science & …, 2023 - Elsevier
Background The integration of CRISPR-Cas systems and surface-enhanced Raman
spectroscopy (SERS) has emerged as a powerful approach for developing highly sensitive …

Prospects of surface-enhanced Raman spectroscopy for biomarker monitoring toward precision medicine

J Plou, PS Valera, I Garcia, CDL de Albuquerque… - ACS …, 2022 - ACS Publications
Future precision medicine will be undoubtedly sustained by the detection of validated
biomarkers that enable a precise classification of patients based on their predicted disease …

Clustered regularly interspaced short palindromic repeats-mediated amplification-free detection of viral DNAs using surface-enhanced Raman spectroscopy-active …

JH Choi, M Shin, L Yang, B Conley, J Yoon, SN Lee… - Acs Nano, 2021 - ACS Publications
Nucleic acid biomarkers have been widely used to detect various viral-associated diseases,
including the recent pandemic COVID-19. The CRISPR-Cas-based trans-activating …