Early mortality among adults accessing antiretroviral treatment programmes in sub-Saharan Africa

SD Lawn, AD Harries, X Anglaret, L Myer, R Wood - Aids, 2008 - journals.lww.com
Two-thirds of the world's HIV-infected people live in sub-Saharan Africa, and more than 1.5
million of them die annually. As access to antiretroviral treatment has expanded within the …

Latent tuberculosis infection: myths, models, and molecular mechanisms

NK Dutta, PC Karakousis - Microbiology and Molecular Biology …, 2014 - Am Soc Microbiol
The aim of this review is to present the current state of knowledge on human latent
tuberculosis infection (LTBI) based on clinical studies and observations, as well as …

Factors associated with virological non-suppression among HIV-positive patients on antiretroviral therapy in Uganda, August 2014–July 2015

L Bulage, I Ssewanyana, V Nankabirwa… - BMC infectious …, 2017 - Springer
Background Despite the growing number of people on antiretroviral therapy (ART), there is
limited information about virological non-suppression and its determinants among HIV …

Earlier versus later start of antiretroviral therapy in HIV-infected adults with tuberculosis

FX Blanc, T Sok, D Laureillard, L Borand… - … England Journal of …, 2011 - Mass Medical Soc
Background Tuberculosis remains an important cause of death among patients infected with
the human immunodeficiency virus (HIV). Robust data are lacking with regard to the timing …

Towards an improved investment approach for an effective response to HIV/AIDS

B Schwartländer, J Stover, T Hallett, R Atun, C Avila… - The Lancet, 2011 - thelancet.com
Substantial changes are needed to achieve a more targeted and strategic approach to
investment in the response to the HIV/AIDS epidemic that will yield long-term dividends …

Development of a standardized screening rule for tuberculosis in people living with HIV in resource-constrained settings: individual participant data meta-analysis of …

H Getahun, W Kittikraisak, CM Heilig, EL Corbett… - PLoS …, 2011 - journals.plos.org
Background The World Health Organization recommends the screening of all people living
with HIV for tuberculosis (TB) disease, followed by TB treatment, or isoniazid preventive …

Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings

G Meintjes, SD Lawn, F Scano, G Maartens… - The Lancet infectious …, 2008 - thelancet.com
The immune reconstitution inflammatory syndrome (IRIS) has emerged as an important early
complication of antiretroviral therapy (ART) in resource-limited settings, especially in …

Isoniazid plus antiretroviral therapy to prevent tuberculosis: a randomised double-blind, placebo-controlled trial

MX Rangaka, RJ Wilkinson, A Boulle, JR Glynn… - The Lancet, 2014 - thelancet.com
Background Antiretroviral therapy reduces the risk of tuberculosis, but tuberculosis is more
common in people with HIV than in people without HIV. We aimed to assess the effect of …

6-month versus 36-month isoniazid preventive treatment for tuberculosis in adults with HIV infection in Botswana: a randomised, double-blind, placebo-controlled trial

T Samandari, TB Agizew, S Nyirenda, Z Tedla… - The Lancet, 2011 - thelancet.com
Background In accordance with WHO guidelines, people with HIV infection in Botswana
receive daily isoniazid preventive therapy against tuberculosis without obtaining a tuberculin …

Diagnostic accuracy of a low-cost, urine antigen, point-of-care screening assay for HIV-associated pulmonary tuberculosis before antiretroviral therapy: a descriptive …

SD Lawn, AD Kerkhoff, M Vogt… - The Lancet infectious …, 2012 - thelancet.com
Background The diagnostic accuracy of sputum smear microscopy and routine chest
radiology for HIV-associated tuberculosis is poor, and culture-based diagnosis is slow …