Bacteriophage therapy against Pseudomonas aeruginosa biofilms: a review

Z Chegini, A Khoshbayan, M Taati Moghadam… - Annals of clinical …, 2020 - Springer
Abstract Multi-Drug Resistant (MDR) Pseudomonas aeruginosa is one of the most important
bacterial pathogens that causes infection with a high mortality rate due to resistance to …

Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process

A Latka, B Maciejewska, G Majkowska-Skrobek… - Applied microbiology …, 2017 - Springer
Bacteriophages are bacterial viruses that infect the host after successful receptor recognition
and adsorption to the cell surface. The irreversible adherence followed by genome material …

Genome-driven elucidation of phage-host interplay and impact of phage resistance evolution on bacterial fitness

P Markwitz, C Lood, T Olszak, V van Noort… - The ISME …, 2022 - academic.oup.com
When considering the interactions between bacteriophages and their host, the issue of
phage-resistance emergence is a key element in understanding the ecological impact of …

Advances in Phage Therapy: Targeting the Burkholderia cepacia Complex

P Lauman, JJ Dennis - Viruses, 2021 - mdpi.com
The increasing prevalence and worldwide distribution of multidrug-resistant bacterial
pathogens is an imminent danger to public health and threatens virtually all aspects of …

Isolation of a bacteriophage targeting Pseudomonas aeruginosa and exhibits a promising in vivo efficacy

A Abdelghafar, A El-Ganiny, G Shaker, M Askoura - AMB Express, 2023 - Springer
Pseudomonas aeruginosa is an important pathogen that causes serious infections. Bacterial
biofilms are highly resistant and render bacterial treatment very difficult, therefore …

The O-specific polysaccharide lyase from the phage LKA1 tailspike reduces Pseudomonas virulence

T Olszak, MM Shneider, A Latka, B Maciejewska… - Scientific reports, 2017 - nature.com
Pseudomonas phage LKA1 of the subfamily Autographivirinae encodes a tailspike protein
(LKA1gp49) which binds and cleaves B-band LPS (O-specific antigen, OSA) of …

Ecology of anti-biofilm agents II: bacteriophage exploitation and biocontrol of biofilm bacteria

ST Abedon - Pharmaceuticals, 2015 - mdpi.com
Bacteriophages are the viruses of bacteria. In the guise of phage therapy they have been
used for decades to successfully treat what are probable biofilm-containing chronic bacterial …

Two novel bacteriophages improve survival in Galleria mellonella infection and mouse acute pneumonia models infected with extensively drug-resistant …

J Jeon, D Yong - Applied and environmental microbiology, 2019 - Am Soc Microbiol
Extensively drug-resistant Pseudomonas aeruginosa (XDR-PA) is a life-threatening
pathogen that causes serious global problems. Here, we investigated two novel P …

Outer Membrane Vesicles (OMVs) of Pseudomonas aeruginosa Provide Passive Resistance but Not Sensitization to LPS-Specific Phages

D Augustyniak, T Olszak, Z Drulis-Kawa - Viruses, 2022 - mdpi.com
Outer membrane vesicles (OMVs) released from gram-negative bacteria are key elements in
bacterial physiology, pathogenesis, and defence. In this study, we investigated the role of …

[HTML][HTML] PhageScore: A simple method for comparative evaluation of bacteriophages lytic activity

M Konopacki, B Grygorcewicz, B Dołęgowska… - Biochemical …, 2020 - Elsevier
Nowadays, an increasing amount of studies indicate the numerous applications of
bacteriophages (eg medical, pharmaceutical, use in animal breeding, food processing) …