Protein-protein and protein-RNA interactions are essential for cell function and survival.
These interactions facilitate the formation of ribonucleoprotein complexes and biomolecular …

Owing to their unique abilities to manipulate, label, and image individual molecules in vitro
and in cellulo, single-molecule techniques provide previously unattainable access to …

Anomalous diffusion, nonergodicity, and ageing for exponentially and logarithmically time-dependent
diffusivity: striking differences for massive versus massless particles - IOPscience This site …

The role of the spatial organization of chromosomes in directing transcription remains an
outstanding question in gene regulation. Here, we analyze two recent single-cell imaging …

We have developed Simulation-based Reconstructed Diffusion (SbRD) to determine
diffusion coefficients corrected for confinement effects and for the bias introduced by two …

Ovoid-shaped bacteria, such as Streptococcus pneumoniae (pneumococcus), have two
spatially separated peptidoglycan (PG) synthase nanomachines that locate zonally to the …

Living systems are studied using three complementary approaches: living cells, cell‐free
systems and computer‐mediated modelling. Progresses in understanding, allowing …

The production of living therapeutics, cell-based delivery of drugs and gene-editing tools
and the manufacturing of bio-commodities all share a common concept: they use either a …

Using optical and electrical methods, we document that diffusion in the cytoplasm of BL6
murine cardiomyocytes becomes restricted> 20-fold as molecular weight increases from 30 …

Bacteria and Archaea are traditionally regarded as organisms with a simple morphology
constrained to a size of 2–3 µm. Nevertheless, the history of microbial research is rich in the …