Flavonoids are a category of plant-derived compounds which exhibit a large number of
health-related effects. One of the most well-known and studied flavonoids is kaempferol …

Background This study describes the spatial and temporal distribution between 2005 and
2020 of human and animal leishmaniasis by Leishmania infantum in European countries …

Background The aim of this study is to describe the major evolutionary historical events
among Leishmania, sandflies, and the associated animal reservoirs in detail, in accordance …

Apigenin is a flavonoid of low toxicity and multiple beneficial bioactivities. Published reviews
all focused on the findings using eukaryotic cells, animal models, or epidemiological studies …

In this review article the history of leishmaniasis is discussed regarding the origin of the
genus Leishmania in the Mesozoic era and its subsequent geographical distribution, initial …

Under physiological conditions, adenosine triphosphate (ATP) is present at low levels in the
extracellular milieu, being massively released by stressed or dying cells. Once outside the …

The evolution of macrophages has made them primordial for both development and
immunity. Their functions range from the shaping of body plans to the ingestion and …

Cutaneous leishmaniasis is a major public health problem and causes a range of diseases
from self-healing infections to chronic disfiguring disease. Currently, there is no vaccine for …

To understand the intricacies of microorganisms at the molecular level requires making
sense of copious volumes of data such that it may now be humanly impossible to detect …

Progress in the diagnosis of leishmaniases depends on the development of effective
methods and the discovery of suitable biomarkers. We propose firstly an update …