[HTML][HTML] Semi-continuous and continuous processes for enantiomeric separation
M Ciriani, R Oliveira, CAM Afonso - Green Chemistry, 2022 - pubs.rsc.org
Chiral resolution is an operation of great interest and increasing importance for the scientific
community and industry. There are two approaches to provide enantiomerically pure …
community and industry. There are two approaches to provide enantiomerically pure …
Single enantiomeric β-blockers—The existing technologies
J Agustian, AH Kamaruddin, S Bhatia - Process Biochemistry, 2010 - Elsevier
A number of β-blocking drugs are available in the world market, only few compounds are
found as single enantiomers. The need to use the single enantiomeric β-blockers affects …
found as single enantiomers. The need to use the single enantiomeric β-blockers affects …
Enantioselective nanofiltration using predictive process modeling: Bridging the gap between materials development and process requirements
Organic solvent nanofiltration (OSN) is a low-energy alternative for continuous separations
in the chemical industry. As the pharmaceutical sector increasingly turns toward continuous …
in the chemical industry. As the pharmaceutical sector increasingly turns toward continuous …
Evaluation of chiral dehydroabietic acid-terminated tetra-arm PEG as an assisted phase-forming polymer and chiral selector for the enantioseparation of propranolol …
Q Liang, L Ge, Q Lu, G Hu, K Yang - Separation and Purification …, 2024 - Elsevier
In this work, we successfully synthesized a chiral dehydroabietic acid-terminated tetra-arm
PEG (4-arm PEG-DHAA) and utilized it to construct a chiral aqueous two-phase system …
PEG (4-arm PEG-DHAA) and utilized it to construct a chiral aqueous two-phase system …
Process optimization of continuous liquid–liquid extraction in centrifugal contactor separators for separation of oxybutynin enantiomers
K Tang, Y Wang, P Zhang, Y Huang, G Dai - Separation and Purification …, 2015 - Elsevier
A model for multistage enantioselective liquid–liquid extraction (ELLE) of oxybutynin (OBN)
enantiomers was built on the basis of single-stage model for chiral extraction of OBN …
enantiomers was built on the basis of single-stage model for chiral extraction of OBN …
Reaction kinetics in reactive extraction for chiral separation of α-cyclohexyl-mandelic acid enantiomers with hydroxypropyl-β-cyclodextrin
K Tang, J Miao, T Zhou, Y Liu, L Song - Chemical engineering science, 2011 - Elsevier
This paper reports on determination of the intrinsic reaction kinetics in reactive extraction of
α-cyclohexyl-mandelic acid (α-CHMA) enantiomers with hydroxypropyl-β-cyclodextrin (HP-β …
α-cyclohexyl-mandelic acid (α-CHMA) enantiomers with hydroxypropyl-β-cyclodextrin (HP-β …
Chiral liquid membrane for enantioselective separation of racemic ibuprofen by l-tartaric acid derivatives
The chirality of drugs plays a significant role in most chemical and biochemical process. In
this paper, a chiral liquid membrane using L-tartaric ester dissolved in n-octane as liquid …
this paper, a chiral liquid membrane using L-tartaric ester dissolved in n-octane as liquid …
Optical Resolution and Optimization of (R,S)‐Propranolol Using Dehydroabietic Acid Via Diastereomeric Crystallization
L Ge, Q Zhao, K Yang, S Liu, F Xia - Chirality, 2015 - Wiley Online Library
The optical resolution of (R, S)‐propranolol by the diastereomeric crystallization method was
successfully performed using dehydroabietic acid (DHAA) as the resolving agent in …
successfully performed using dehydroabietic acid (DHAA) as the resolving agent in …
Thiols׳ extraction from “jet-fuel” assisted by ionic liquids in hollow fibre membrane contactors
AR Ferreira, LA Neves, JC Ribeiro, FM Lopes… - Journal of Membrane …, 2015 - Elsevier
This work proposes an alternative technique for the selective extraction of thiols from a “jet-
fuel” model stream, using the 1-ethyl-3-methylimidazolium triflate ([C 2 mim][CF 3 SO 3]) …
fuel” model stream, using the 1-ethyl-3-methylimidazolium triflate ([C 2 mim][CF 3 SO 3]) …
PEG600‐Carboxylates as Efficient Reusable Reaction Media and Acylating Agents for the Resolution of sec‐Alcohols
CM Monteiro, NMT Lourenço, FC Ferreira… - …, 2015 - Wiley Online Library
Herein is presented a simple, attractive, and reusable methodology for one‐pot
resolution/separation of free sec‐alcohols with enantiomeric excess (ee) values over 90 …
resolution/separation of free sec‐alcohols with enantiomeric excess (ee) values over 90 …