Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy
Hepatocellular carcinoma (HCC) mortality rates are increasing globally, and particularly in
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …
The Future Role of Abdominal US in Hepatocellular Carcinoma Surveillance
Abdominal US is currently the best-validated surveillance strategy for hepatocellular
carcinoma (HCC) in at-risk patients. It is the only modality shown to have completed all five …
carcinoma (HCC) in at-risk patients. It is the only modality shown to have completed all five …
Hepatocellular carcinoma surveillance patterns and outcomes in patients with cirrhosis
D Daher, KS El Dahan, A Cano, M Gonzales… - Clinical …, 2024 - Elsevier
Background & Aims Hepatocellular carcinoma (HCC) surveillance is associated with
improved early detection and reduced mortality, although practice patterns and effectiveness …
improved early detection and reduced mortality, although practice patterns and effectiveness …
The financial burden after liver transplantation is significant among commercially insured adults: A large US National Cohort
Liver transplantation (LT) is lifesaving for patients with cirrhosis; however, the resultant
financial burden to patients has not been well characterized. We aimed to provide a …
financial burden to patients has not been well characterized. We aimed to provide a …
Hepatocellular Carcinoma Screening in a Contemporary Cohort of At-Risk Patients
Importance Cohort studies demonstrating an association of hepatocellular carcinoma (HCC)
screening with reduced mortality are prone to lead-time and length-time biases. Objective To …
screening with reduced mortality are prone to lead-time and length-time biases. Objective To …
Cost-Effectiveness of a Biomarker-Based Screening Strategy for Hepatocellular Carcinoma in Patients with Cirrhosis
Introduction: Given suboptimal performance of ultrasound-based surveillance for early
hepatocellular carcinoma (HCC) detection in patients with cirrhosis, there is interest in …
hepatocellular carcinoma (HCC) detection in patients with cirrhosis, there is interest in …
Benefits and Harms of Hepatocellular Carcinoma Screening Outreach in Patients with Cirrhosis: A Multi-Center Randomized Clinical Trial
Background The value of hepatocellular carcinoma (HCC) screening is defined by the
balance of benefits from early tumor detection vs harms due to false positive results. We …
balance of benefits from early tumor detection vs harms due to false positive results. We …
HES V2. 0 outperforms GALAD for detection of HCC: A phase 3 biomarker study in the United States
Background: The original hepatocellular carcinoma early detection screening (HES) score,
which combines alpha-fetoprotein (AFP) with age, alanine aminotransferase, and platelets …
which combines alpha-fetoprotein (AFP) with age, alanine aminotransferase, and platelets …
Proportion time covered by hepatocellular carcinoma surveillance in patients with cirrhosis
D Daher, KS El Dahan, S Yekkaluri… - Official journal of the …, 2022 - journals.lww.com
Background: Hepatocellular carcinoma (HCC) surveillance is associated with improved
early tumor detection, but effectiveness is limited by underuse. We characterized adherence …
early tumor detection, but effectiveness is limited by underuse. We characterized adherence …
Pragmatic strategies to address health disparities along the continuum of care in chronic liver disease
Racial, ethnic, and socioeconomic disparities exist in the prevalence and natural history of
chronic liver disease, access to care, and clinical outcomes. Solutions to improve health …
chronic liver disease, access to care, and clinical outcomes. Solutions to improve health …