The human tissue kallikrein gene family was, until recently, thought to consist of only three
genes. Two of these human kallikreins, prostate-specific antigen and human glandular …

The 15 members of the kallikrein-related serine peptidase (KLK) family have diverse tissue-
specific expression profiles and putative proteolytic functions. The kallikrein family is also …

Tissue kallikreins are members of the S1 family (clan SA) of trypsin-like serine proteases
and are present in at least six mammalian orders. In humans, tissue kallikreins (hK) are …

Kallikreins are a subgroup of the serine protease enzyme family. Until recently, it was
thought that the human kallikrein gene family contained only three members. In the past 3 …

The traditional human kallikrein gene family consists of three genes, namely KLK1
[encoding human kallikrein 1 (hK1) or pancreatic/renal kallikrein], KLK2 (encoding hK2 …

Prostate specific antigen (PSA) or human kallikrein 3 (hK3) has long been an effective
biomarker for prostate cancer. Now, other members of the tissue kallikrein (KLK) gene family …

Many serine proteases play important regulatory roles in complex biological systems, but
only a few have been linked directly with capillary morphogenesis and angiogenesis. Here …

Kallikreins are a subgroup of serine proteases with diverse physiological functions.
Recently, growing evidence indicates that many kallikrein genes are involved in malignancy …

Human tissue kallikreins (KLKs) are attracting increased attention due to their role as
biomarkers for the screening, diagnosis, prognosis, and monitoring of various cancers …

Accumulation of insoluble alpha-synuclein aggregates in the brain is characteristic of
Parkinson's disease, dementia with Lewy bodies and multiple system atrophy. Although …