The term 'mechanosensation'describes the capacity of cells to translate mechanical stimuli
into the coordinated regulation of intracellular signals, cellular function, gene expression …

Background: Conversion of cardiac stromal cells into myofibroblasts is typically associated
with hypoxia conditions, metabolic insults, and/or inflammation, all of which are predisposing …

Background and objective The diagnosis of histopathological images is based on the visual
analysis of tissue slices under a light microscope. However, the histological tissue …

Multiplexed fluorescence in situ hybridization techniques have enabled cell-type
identification, linking transcriptional heterogeneity with spatial heterogeneity of cells …

Skeletal muscle is an adaptive tissue with the ability to regenerate in response to exercise
training. Cross-sectional area (CSA) quantification, as a main parameter to assess muscle …

Dataset annotation is a time and labor-intensive task and an integral requirement for training
and testing deep learning models. The segmentation of images in life science microscopy …

Tissue decellularization is typically assessed through absorbance-based DNA quantification
after tissue digestion. This method has several disadvantages, namely its destructive nature …

Despite the use of multimodal treatment combinations, the prognosis of glioblastoma (GB) is
still poor. To prevent rapid tumor recurrence, targeted strategies for the treatment of GB are …

Unbiased evaluation of morphology is crucial to understanding development, mechanics,
and pathology of striated muscle tissues. Indeed, the ability of striated muscles to contract …

Background and objectives In breast carcinoma, epithelial–stromal interactions play a
pivotal role in tumor formation and progression, and it must be accurately assessed for a …