Materials for oral delivery of proteins and peptides

TD Brown, KA Whitehead, S Mitragotri - Nature Reviews Materials, 2020 - nature.com
Throughout history, oral administration has been regarded as the most convenient mode of
drug delivery, as it requires minimal expertise and invasiveness. Although oral delivery …

Oral drug delivery platforms for biomedical applications

J Ouyang, Z Zhang, B Deng, J Liu, L Wang, H Liu… - Materials Today, 2023 - Elsevier
Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …

Nanoparticle-based therapeutic approaches for wound healing: a review of the state-of-the-art

BHJ Gowda, S Mohanto, A Singh, A Bhunia… - Materials Today …, 2023 - Elsevier
Wound healing is a complex physiological procedure that includes diverse stages,
comprising hemostasis, inflammation, proliferation, and remodeling to reconstruct the skin …

Evolution of insulin delivery devices: from syringes, pens, and pumps to DIY artificial pancreas

J Kesavadev, B Saboo, MB Krishna, G Krishnan - Diabetes Therapy, 2020 - Springer
The year 2021 will mark 100 years since the discovery of insulin. Insulin, the first medication
to be discovered for diabetes, is still the safest and most potent glucose-lowering therapy …

Insulin delivery systems combined with microneedle technology

X Jin, DD Zhu, BZ Chen, M Ashfaq, XD Guo - Advanced drug delivery …, 2018 - Elsevier
Diabetes, a metabolic disorder of glucose, is a serious chronic disease and an important
public health problem. Insulin is one of the hormones for modulating blood glucose level …

Identification of barriers to insulin therapy and approaches to overcoming them

D Russell‐Jones, F Pouwer… - Diabetes, Obesity and …, 2018 - Wiley Online Library
Poor glycaemic control in type 2 diabetes (T2D) is a global problem despite the availability
of numerous glucose‐lowering therapies and clear guidelines for T2D management …

Nanoparticles-encapsulated polymeric microneedles for transdermal drug delivery

M Chen, G Quan, Y Sun, D Yang, X Pan… - Journal of Controlled …, 2020 - Elsevier
Polymeric microneedles (MNs) have been leveraged as a novel transdermal drug delivery
platform for effective drug permeation, which were widely used in the treatment of various …

Therapies for type 1 diabetes: current scenario and future perspectives

V Pathak, NM Pathak, CL O'Neill… - Clinical Medicine …, 2019 - journals.sagepub.com
Type 1 diabetes (T1D) is caused by autoimmune destruction of insulin-producing β cells
located in the endocrine pancreas in areas known as islets of Langerhans. The current …

Scalable fabrication of size-controlled chitosan nanoparticles for oral delivery of insulin

Z He, JL Santos, H Tian, H Huang, Y Hu, L Liu… - Biomaterials, 2017 - Elsevier
Controlled delivery of protein would find diverse therapeutic applications. Formulation of
protein nanoparticles by polyelectrolyte complexation between the protein and a natural …

Biomedical applications of polysaccharide nanoparticles for chronic inflammatory disorders: Focus on rheumatoid arthritis, diabetes and organ fibrosis

P Allawadhi, V Singh, K Govindaraj, I Khurana… - Carbohydrate …, 2022 - Elsevier
Polysaccharides are biopolymers distinguished by their complex secondary structures
executing various roles in microorganisms, plants, and animals. They are made up of long …